Ganio Matthew S, Armstrong Lawrence E, Johnson Evan C, Klau Jennifer F, Ballard Kevin D, Michniak-Kohn Bozena, Kaushik Diksha, Maresh Carl M
Human Performance Laboratory, University of Connecticut, Storrs, CT, USA.
J Sports Sci. 2010 Jan;28(2):201-8. doi: 10.1080/02640410903428558.
Quercetin is a naturally occurring flavonoid with anti-oxidant and anti-inflammatory properties. The effect of quercetin supplementation on maximal oxygen uptake (VO(2max)) is unknown. The purpose of this investigation was to test the effects of quercetin supplementation on VO(2max) in untrained, sedentary individuals. After baseline treadmill VO(2max) testing, 11 participants (5 males, 6 females) ingested either placebo or quercetin-supplemented (1000 mg x day(-1)) food bars in a randomized, double-blind, counterbalanced, crossover research design. The participants ingested food bars for six consecutive mornings (5 days). On the sixth morning, participants underwent repeat VO(2max) testing. After a 22 day wash-out, the participants repeated baseline VO(2max) testing, daily consumption of the opposite food bars, and post-supplementation VO(2max) testing. The condition x time interaction for VO(2max) was non-significant when expressed in absolute (litres x min(-1); P = 0.929) and relative (ml x kg(-1) x min(-1); P = 0.778) terms. These findings were similar when taking sex into account (P > 0.05). The mean difference in VO(2max) change from pre to post between groups (quercetin vs. placebo) was 0.139 ml x kg(-1) x min(-1) (P = 0.780). Other physiological measures also were similar between conditions (P > 0.05). In conclusion, 5 days of quercetin supplementation did not influence VO(2max) or related variables in sedentary men and women.
槲皮素是一种天然存在的具有抗氧化和抗炎特性的类黄酮。补充槲皮素对最大摄氧量（VO₂max）的影响尚不清楚。本研究的目的是测试补充槲皮素对未经训练的久坐不动个体的VO₂max的影响。在进行基线跑步机VO₂max测试后，11名参与者（5名男性，6名女性）采用随机、双盲、平衡、交叉研究设计，摄入安慰剂或补充槲皮素（1000毫克/天⁻¹）的食物棒。参与者连续六个早晨（5天）摄入食物棒。在第六个早晨，参与者接受重复的VO₂max测试。经过22天的洗脱期后，参与者重复基线VO₂max测试、每天摄入相反的食物棒以及补充后VO₂max测试。当以绝对（升/分钟；P = 0.929）和相对（毫升/千克⁻¹/分钟；P = 0.778）单位表示时，VO₂max的条件×时间交互作用不显著。考虑性别因素时，这些结果相似（P > 0.05）。两组（槲皮素组与安慰剂组）从预测试到后测试的VO₂max变化的平均差异为0.139毫升/千克⁻¹/分钟（P = 0.780）。其他生理指标在不同条件下也相似（P > 0.05）。总之，补充5天槲皮素对久坐不动的男性和女性的VO₂max或相关变量没有影响。
