Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, 226031, India.
Department of Pharmacy, Banasthali Vidyapith, Banasthali, Rajasthan, 304022, India.
AAPS PharmSciTech. 2024 Feb 29;25(3):51. doi: 10.1208/s12249-024-02761-6.
The term cosmetics refers to any substances or products intended for external application on the skin with the aim of protection and better appearance of the skin surface. The skin delivery system promotes the controlled and targeted delivery of active ingredients. The development of this system has been driven by challenges encountered with conventional cosmeceuticals, including low skin retention of active components, limited percutaneous penetration, poor water dispersion of insoluble active ingredients, and instability of effective components. The aim is to create cosmeceuticals that can effectively overcome these issues. This review focuses on various nanocarriers used in cosmeceuticals currently and their applications in skin care, hair care, oral care, and more. The importance of nanotechnology in the sphere of research and development is growing. It provides solutions to various problems faced by conventional technologies, methods, and product formulations thus taking hold of the cosmetic industry as well. Nowadays, consumers are investing in cosmetics only for better appearance thus problems like wrinkles, ageing, hair loss, and dandruff requires to be answered proficiently. Nanocarriers not only enhance the efficacy of cosmeceutical products, providing better and longer-lasting effects, but they also contribute to the improved aesthetic appearance of the products. This dual benefit not only enhances the final quality and efficacy of the product but also increases consumer satisfaction. Additionally, nanocarriers offer protection against UV rays, further adding to the overall benefits of the cosmeceutical product. Figure 1 represents various advantages of nanocarriers used in cosmeceuticals. Nanotechnology is also gaining importance due to their high penetration of actives in the deeper layers of skin. It can be said that nanotechnology is taking over all the drawbacks of the traditional products. Thus, nanocarriers discussed in this review are used in nanotechnology to deliver the active ingredient of the cosmeceutical product to the desired site.
术语“化妆品”是指任何旨在保护和改善皮肤表面外观的、用于皮肤外部涂抹的物质或产品。皮肤传递系统促进了活性成分的控制和靶向传递。该系统的开发是为了应对传统化妆品所面临的挑战,包括活性成分在皮肤中的低保留率、有限的经皮渗透、不溶性活性成分的差水分散性以及有效成分的不稳定性。其目的是创造能够有效克服这些问题的化妆品。本文重点介绍了目前在化妆品中使用的各种纳米载体及其在皮肤护理、头发护理、口腔护理等方面的应用。纳米技术在研究和开发领域的重要性日益增加。它为传统技术、方法和产品配方所面临的各种问题提供了解决方案,因此也抓住了化妆品行业。如今,消费者只为了更好的外观而投资于化妆品,因此需要有效地解决皱纹、衰老、脱发和头皮屑等问题。纳米载体不仅增强了化妆品的功效,提供了更好、更持久的效果,而且还改善了产品的美学外观。这种双重效益不仅提高了产品的最终质量和功效,也提高了消费者的满意度。此外,纳米载体还能提供对紫外线的防护,进一步增加了化妆品的整体效益。图 1 表示了化妆品中使用的纳米载体的各种优势。由于其对皮肤深层活性成分的高渗透性,纳米技术也变得越来越重要。可以说,纳米技术正在克服传统产品的所有缺点。因此,本文讨论的纳米载体被用于纳米技术,将化妆品产品的活性成分递送到所需的部位。