McClure R D, Khoo D, Jarvi K, Hricak H
Department of Urology, University of California School of Medicine, San Francisco 94143-0738.
J Urol. 1991 Apr;145(4):789-91. doi: 10.1016/s0022-5347(17)38452-5.
To investigate the controversial concept that subclinical varicoceles are detrimental to spermatogenesis, we undertook a prospective study of the effectiveness of surgery in 56 infertile men with clinical and subclinical varicoceles. Our statistical approach specifies improvement as a change from individual baseline level. The over-all variability in sperm counts precluded the demonstration of significant changes in sperm density consequent to surgery. Improvement in sperm motility was seen in both groups, being slightly greater in the subclinical group. The changes were inversely related to baseline levels and increased with time from surgery. Therefore, it appears that the detection of subclinical varicoceles may be warranted in infertile men with abnormal semen parameters.
为了研究亚临床精索静脉曲张对精子发生有害这一有争议的概念，我们对56例患有临床和亚临床精索静脉曲张的不育男性进行了一项关于手术疗效的前瞻性研究。我们的统计方法将改善定义为相对于个体基线水平的变化。精子计数的总体变异性使得无法证明手术后精子密度有显著变化。两组患者的精子活力均有改善，亚临床组的改善略大。这些变化与基线水平呈负相关，并随手术后时间的延长而增加。因此，对于精液参数异常的不育男性，似乎有必要检测亚临床精索静脉曲张。
