Center for Diseases Control of Jiangsu Province, Nanjing, China.
Circ J. 2010 Mar;74(3):456-61. doi: 10.1253/circj.cj-09-0422. Epub 2010 Jan 7.
Few prospective studies have explored blood pressure (BP) and other components of the metabolic syndrome (MetS) and their interaction in the development of cardiovascular diseases (CVD) in China.
A prospective study of the prevention of multiple metabolic disorders and MetS in Jiangsu province, China: 3,598 subjects were followed for a median of 6.3 years. The Asian criterion of the National Cholesterol Education Program Adult Treatment Panel III was used to define the MetS. Independent risk of the MetS and its components on developing CVD was analyzed, but only BP was associated with CVD. Incidence and risk of CVD increased with the number of MetS components. A linear association was found between the risk of CVD, BP and the number of other components (trend, P<0.01). The adjusted relative risk of developing CVD was increased when BP and other components coexisted. However, the interaction of BP and other components of MetS was not significant (P>0.05).
In Chinese, among the components of MetS BP was an independent risk factor for CVD. No significant interaction was found between BP and the other MetS components.
很少有前瞻性研究探讨中国人群中血压（BP）和代谢综合征（MetS）的其他成分及其相互作用与心血管疾病（CVD）的发展之间的关系。
中国江苏省预防多种代谢紊乱和代谢综合征的前瞻性研究：3598 例受试者的中位随访时间为 6.3 年。采用国家胆固醇教育计划成人治疗专家组 III 的亚洲标准来定义代谢综合征。分析了代谢综合征及其成分对发生 CVD 的独立风险，但只有 BP 与 CVD 相关。随着 MetS 成分数量的增加，CVD 的发生率和风险增加。在 CVD、BP 和其他成分的数量之间发现了线性关联（趋势，P<0.01）。当 BP 和其他 MetS 成分共存时，发生 CVD 的调整相对风险增加。然而，BP 和 MetS 的其他成分之间的相互作用不显著（P>0.05）。
在中国人中，MetS 的成分中 BP 是 CVD 的独立危险因素。BP 和其他 MetS 成分之间没有发现显著的相互作用。
