School of Women's and Infants' Health, University of Western Australia, and Women and Infants Research Foundation, King Edward Memorial Hospital, Perth, Western Australia, Australia.
Fertil Steril. 2010 Aug;94(3):1118-21. doi: 10.1016/j.fertnstert.2009.11.002. Epub 2010 Jan 8.
Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in adolescents, with potentially significant lifelong consequences. This prospective study set out to determine if the investigators could derive a threshold value of antimullerian hormone (AMH) that would predict its presence according to two internationally recognized definitions using a simple measurement, avoiding more extensive and potentially more invasive investigations. The study failed to demonstrate, in a general adolescent population, that serum AMH is a reliable predictor of PCO morphology or for the presence of PCOS.
多囊卵巢综合征(PCOS)是青少年常见的内分泌疾病,可能会产生重大的终身影响。本前瞻性研究旨在确定研究人员能否通过简单的测量得出抗缪勒管激素(AMH)的阈值,根据两种国际公认的定义来预测其存在,避免更广泛和潜在更具侵袭性的检查。该研究未能证明,在一般的青少年人群中,血清 AMH 是多囊卵巢形态或 PCOS 存在的可靠预测指标。