血管紧张素 II 受体拮抗剂治疗妊娠期偏头痛：致死结局。
Angiotensin II receptor antagonists against migraine in pregnancy: fatal outcome.
机构信息
Department of Pediatrics, Oslo University Hospital, Ullevål, Oslo, Norway.
出版信息
J Headache Pain. 2010 Apr;11(2):167-9. doi: 10.1007/s10194-009-0182-7.
Abstract
A pregnant young woman with a severe migraine is prescribed candesartan, an angiotensin II type 1 receptor antagonist (AT II antagonists). This has a positive effect-except for severe maldevelopment of her fetus. There is an increase in the use of the fetotoxic drugs, AT II antagonists and angiotensin-converting enzyme inhibitors, as prophylactic treatment of migraines, in addition to their use as hypertensives.
摘要
一位患有严重偏头痛的年轻孕妇被开了坎地沙坦，一种血管紧张素 II 型 1 型受体拮抗剂（AT II 拮抗剂）。这有积极的效果——除了她胎儿的严重发育不良。血管紧张素 II 拮抗剂和血管紧张素转换酶抑制剂作为偏头痛的预防治疗药物的使用增加了，除了它们作为高血压药物的使用。
相似文献
1
Angiotensin II receptor antagonists against migraine in pregnancy: fatal outcome.血管紧张素 II 受体拮抗剂治疗妊娠期偏头痛：致死结局。
J Headache Pain. 2010 Apr;11(2):167-9. doi: 10.1007/s10194-009-0182-7.
2
Teratogenicity with angiotensin II receptor antagonists in pregnancy.孕期使用血管紧张素II受体拮抗剂的致畸性。
J Endocrinol Invest. 2005 Dec;28(11):1029-31. doi: 10.1007/BF03345344.
3
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for the prevention of migraines.血管紧张素转化酶抑制剂和血管紧张素受体阻滞剂预防偏头痛。
Ann Pharmacother. 2010 Feb;44(2):360-6. doi: 10.1345/aph.1M312. Epub 2010 Jan 19.
4
5
[Cross reactivity between ACE inhibitors and angiotensin receptor blockers].[血管紧张素转换酶抑制剂与血管紧张素受体阻滞剂之间的交叉反应]
Lakartidningen. 2010;107(7):444.
6
Increased renal echogenicity in a preterm neonate. Kidneys with tubular dysplasia due to exposure to candesartan during pregnancy.一名早产儿肾回声增强。因孕期接触坎地沙坦导致肾小管发育异常的肾脏。
Pediatr Nephrol. 2005 Nov;20(11):1664-5, 1666-8. doi: 10.1007/s00467-005-1937-2. Epub 2005 Aug 5.
7
Oligohydramnios and pulmonary hypoplasia: a case in which involvement of an angiotensin II receptor antagonist was suspected.羊水过少与肺发育不全：一例怀疑血管紧张素 II 受体拮抗剂与之有关的病例。
J Obstet Gynaecol Res. 2008 Apr;34(2):242-6. doi: 10.1111/j.1447-0756.2008.00762.x.
8
Angiotensin II receptor blocker induced fetopathy: 7 cases.血管紧张素II受体阻滞剂致胎儿病：7例
Klin Padiatr. 2011 Jan;223(1):10-4. doi: 10.1055/s-0030-1269895. Epub 2011 Jan 26.
9
Severe neonatal renal failure after maternal use of angiotensin II type I receptor antagonists.母亲使用血管紧张素II 1型受体拮抗剂后出现的严重新生儿肾衰竭。
Pediatr Med Chir. 2008 Nov-Dec;30(6):306-8.
10
[Fetal toxicity of angiotensin-II receptor antagonists].[血管紧张素 II 受体拮抗剂的胎儿毒性]
J Gynecol Obstet Biol Reprod (Paris). 2006 Nov;35(7):729-31. doi: 10.1016/s0368-2315(06)76471-7.
引用本文的文献
1
Exposure to medication for neurological disease in pregnancy - time to consider the long-term implications?孕期接触治疗神经疾病的药物——是时候考虑其长期影响了吗？
EClinicalMedicine. 2023 Aug 24;63:102157. doi: 10.1016/j.eclinm.2023.102157. eCollection 2023 Sep.
2
Candesartan Does Not Activate PPARγ and Its Target Genes in Early Gestation Trophoblasts.坎地沙坦不会激活早期妊娠滋养层细胞中的 PPARγ 及其靶基因。
Int J Mol Sci. 2022 Oct 14;23(20):12326. doi: 10.3390/ijms232012326.
3
Evaluation of Antioxidant Therapeutic Value of ACE Inhibitor as Adjunct Therapy on Type 2 Diabetes Mellitus Patients with Cardiovascular Disease.评估血管紧张素转换酶抑制剂作为辅助治疗对患有心血管疾病的2型糖尿病患者的抗氧化治疗价值。
ACS Pharmacol Transl Sci. 2022 May 11;5(6):413-418. doi: 10.1021/acsptsci.1c00269. eCollection 2022 Jun 10.
4
Outcomes of 83 fetuses exposed to angiotensin receptor blockers during the second or third trimesters: a literature review.在妊娠第二或第三 trimester 期间接触血管紧张素受体阻滞剂的 83 例胎儿的结局：文献综述。
Hypertens Res. 2015 May;38(5):308-13. doi: 10.1038/hr.2015.12. Epub 2015 Feb 19.
5
Angiotensin-II receptor 1 antagonist fetopathy--risk assessment, critical time period and vena cava thrombosis as a possible new feature.血管紧张素-Ⅱ受体 1 拮抗剂胎儿病——风险评估、关键时期和腔静脉血栓形成可能是新的特征。
Br J Clin Pharmacol. 2013 Mar;75(3):822-30. doi: 10.1111/j.1365-2125.2012.04388.x.
6
Exposure to candesartan during the first trimester of pregnancy in type 1 diabetes: experience from the placebo-controlled DIabetic REtinopathy Candesartan Trials.在 1 型糖尿病患者妊娠早期接触坎地沙坦：来自安慰剂对照的糖尿病视网膜病变坎地沙坦试验的经验。
Diabetologia. 2011 Jun;54(6):1298-303. doi: 10.1007/s00125-010-2040-1. Epub 2011 Jan 12.
本文引用的文献
1
Migraine prophylaxis.偏头痛预防
Med J Aust. 2008 Sep 1;189(5):283-8. doi: 10.5694/j.1326-5377.2008.tb02028.x.
2
Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney.孕期抑制血管紧张素 II 受体可导致发育中的大鼠肾脏出现畸形。
Eur J Pharmacol. 2008 Jun 24;588(1):114-23. doi: 10.1016/j.ejphar.2008.04.014. Epub 2008 Apr 9.
3
Oligohydramnios and pulmonary hypoplasia: a case in which involvement of an angiotensin II receptor antagonist was suspected.羊水过少与肺发育不全：一例怀疑血管紧张素 II 受体拮抗剂与之有关的病例。
J Obstet Gynaecol Res. 2008 Apr;34(2):242-6. doi: 10.1111/j.1447-0756.2008.00762.x.
4
Current trends in migraine prophylaxis.偏头痛预防的当前趋势。
Headache. 2007 Apr;47 Suppl 1:S52-7. doi: 10.1111/j.1526-4610.2007.00677.x.
5
EFNS guideline on the drug treatment of migraine - report of an EFNS task force.欧洲神经科学联合会偏头痛药物治疗指南——欧洲神经科学联合会特别工作组报告
Eur J Neurol. 2006 Jun;13(6):560-72. doi: 10.1111/j.1468-1331.2006.01411.x.
6
Renal tubular dysgenesis, a not uncommon autosomal recessive disorder leading to oligohydramnios: Role of the Renin-Angiotensin system.肾小管发育不全，一种导致羊水过少的常染色体隐性疾病：肾素 - 血管紧张素系统的作用
J Am Soc Nephrol. 2006 Aug;17(8):2253-63. doi: 10.1681/ASN.2005121303. Epub 2006 Jun 21.
7
Medications for migraine prophylaxis.偏头痛预防性药物。
Am Fam Physician. 2006 Jan 1;73(1):72-8.
8
Developmental toxicity of the angiotensin II type 1 receptor antagonists during human pregnancy: a report of 10 cases.血管紧张素II 1型受体拮抗剂在人类孕期的发育毒性：10例报告
BJOG. 2005 Jun;112(6):710-2. doi: 10.1111/j.1471-0528.2004.00525.x.
9
Efficacy of candesartan in the treatment of migraine in hypertensive patients.坎地沙坦治疗高血压患者偏头痛的疗效。
Hypertens Res. 2004 Jun;27(6):441-6. doi: 10.1291/hypres.27.441.
10
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.用血管紧张素 II 受体阻滞剂预防性治疗偏头痛：一项随机对照试验。
JAMA. 2003 Jan 1;289(1):65-9. doi: 10.1001/jama.289.1.65.
Zotero 插件