Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden.
Scand J Rheumatol. 2010 May;39(3):223-8. doi: 10.3109/03009740903347975.
The Psoriatic Arthritis Quality of Life (PsAQoL) questionnaire is the first disease-specific patient-derived instrument for assessing QoL in patients with PsA and has been extensively validated in this population. The aim of the adaptation process reported here was to develop a Swedish version of the PsAQoL that was equivalent to, and met the same psychometric and acceptability standards as, the original instrument, which was developed in the UK.
Translation of the original questionnaire into Swedish was performed by a professional and a lay panel. Field testing for face and content validity was performed by interviewing 13 patients. Finally, 123 patients with PsA were included in a test-retest postal survey designed to test reproducibility and construct validity. The PsAQoL was administered on two occasions approximately 2 weeks apart. The Nottingham Health Profile (NHP) was used as a comparator instrument.
The Swedish version of the PsAQoL questionnaire showed good reliability at both time points and, as expected, correlated with the NHP. The scale was able to distinguish between groups based on self-reported general health and flare-up. Patients with active symptoms of both arthritis and psoriasis had worse QoL. The results also indicated that duration of disease has a progressive impact on PsAQoL scores.
This study provides evidence that the adapted PsAQoL can be used for clinical studies in Swedish patients. The instrument provides valuable information on the long-term effects of PsA on QoL.
银屑病关节炎生活质量问卷（PsAQoL）是首个用于评估银屑病关节炎患者生活质量的疾病特异性患者衍生工具，已在该人群中得到广泛验证。本报告中适应过程的目的是开发一种与原始工具等效的瑞典语版 PsAQoL，且符合原始工具的相同心理测量学和可接受性标准，该原始工具由英国开发。
通过专业和非专业小组将原始问卷翻译成瑞典语。通过对 13 名患者进行访谈，对表面效度和内容效度进行了现场测试。最后，对 123 名银屑病关节炎患者进行了两次测试-重测的邮寄调查，旨在测试可重复性和结构效度。两次测试大约间隔两周，分别对 PsAQoL 进行评估。诺丁汉健康状况调查问卷（NHP）作为比较工具。
瑞典语版 PsAQoL 问卷在两个时间点均显示出良好的可靠性，且与 NHP 相关。该量表能够根据自我报告的总体健康状况和病情加重来区分不同组别。同时患有关节炎和银屑病症状的患者生活质量更差。结果还表明，疾病持续时间对 PsAQoL 评分有渐进性影响。
本研究为瑞典患者的临床研究提供了使用适应后的 PsAQoL 的证据。该工具提供了有关银屑病关节炎对生活质量的长期影响的有价值的信息。
