Health and Exercise Sciences, School of Science and Technology, University of the West of Scotland, Hamilton, UK.
BMC Public Health. 2010 Jan 8;10:8. doi: 10.1186/1471-2458-10-8.
Cardiovascular disease (CVD) is the main cause of mortality throughout the world. With accumulating evidence suggesting that CVD has its origins in childhood, it is unsurprising that research into obesity prevalence within school aged youth is burgeoning. Within this study our primary objective will be to examine whether high intensity interval training (HIT) improves the CVD risk profile of secondary school aged adolescents. Our secondary objective will be to identify the prevalence of CVD risk factors and examine factors associated with these in adolescents aged 15-18 years.
METHOD/DESIGN: A South Lanarkshire school of low socioeconomic status (SES) was selected to participate in the study intervention. Participants from secondary 5 (15-17 years) and 6 (16-18 years) will be recruited for this study. Participants from secondary 6 will be randomly assigned to Group A (HIT) or Group B (moderate-vigorous) and will perform each protocol three times weekly. The secondary 5 participants will act as the control group. Data collection will take place during the Physical Education (PE) lessons and on school premises and will include: anthropometrical variables (height, weight, waist and hip circumferences, skinfold thickness at two sites), physiological responses (blood pressure, aerobic fitness, heart rate (HR) response, vertical jump performance, 10-metre (m) sprint, 50-m sprint and 505-agility test), diet (self-reported seven-day food diary), physical activity (Physical Activity Questionnaire for Adolescents (PAQ-A)) and blood tests (fasting glucose, insulin, total cholesterol (TC), high-density lipoprotein (HDL), high-sensitivity C-reactive protein (hs-CRP), fibrinogen (Fg), interleukin-6 (IL-6), adiponectin (high molecular weight), triglyceride and plasminogen activator inhibitor-1 (PAI-1). An environmental audit of the secondary school and the health related quality of life (HRQOL) of the participants will also be measured. Finally, all exercise sessions will be video recorded and rate of perceived exertion (RPE) and mood states will also be taken after each exercise session.
Our study may be able to demonstrate a time efficient means of reducing CVD risk factors in adolescents.
NCT01027156.
心血管疾病（CVD）是全球范围内主要的死亡原因。随着越来越多的证据表明 CVD 起源于儿童期，因此对学龄青少年肥胖患病率的研究也在不断增加。在本研究中，我们的主要目标是研究高强度间歇训练（HIT）是否能改善青少年的 CVD 风险状况。我们的次要目标是确定 CVD 风险因素的流行情况，并研究 15-18 岁青少年中与这些因素相关的因素。
方法/设计：选择一所社会经济地位（SES）较低的南拉纳克郡中学参与研究干预。将从 5 年级（15-17 岁）和 6 年级（16-18 岁）招募参与者参加本研究。将 6 年级的参与者随机分配到 A 组（HIT）或 B 组（中-高强度），并每周进行三次每种方案的训练。5 年级的参与者将作为对照组。数据收集将在体育课上和学校内进行，包括：人体测量学变量（身高、体重、腰围和臀围、两个部位的皮褶厚度）、生理反应（血压、有氧适能、心率（HR）反应、垂直跳跃表现、10 米冲刺、50 米冲刺和 505 敏捷测试）、饮食（自我报告的 7 天食物日记）、体力活动（青少年体力活动问卷（PAQ-A））和血液测试（空腹血糖、胰岛素、总胆固醇（TC）、高密度脂蛋白（HDL）、高敏 C 反应蛋白（hs-CRP）、纤维蛋白原（Fg）、白细胞介素-6（IL-6）、脂联素（高分子量）、甘油三酯和纤溶酶原激活物抑制剂-1（PAI-1））。还将对中学进行环境审计，并测量参与者的健康相关生活质量（HRQOL）。最后，将对所有运动课程进行视频记录，并在每次运动课程后测量感知用力程度（RPE）和情绪状态。
我们的研究也许能够证明一种高效的方法，可用于减少青少年的 CVD 风险因素。
NCT01027156。
