Jackson Gregory R, Edwards John G
J Ocul Biol Dis Infor. 2008 Mar;1(1):7-11. doi: 10.1007/s12177-008-9002-6. Epub 2008 May 6.
Dark adaptometry may be a useful diagnostic test and clinical trial endpoint for age-related maculopathy (ARM) because impaired night vision is a hallmark of early ARM. A novel dark adaptometer, the AdaptDx, was evaluated for the detection of ARM. The AdaptDx incorporates a 20-minute protocol optimized for the detection of ARM. ARM patients (N = 17) exhibited substantial dark adaptation impairment compared with normal adults (N = 17). The diagnostic sensitivity was 88% and the specificity was 100%. The diagnostic test characteristics of the AdaptDx are similar to previously reported studies using 60- to 120-minute protocols.
暗适应测量法可能是一种用于年龄相关性黄斑病变（ARM）的有用诊断测试和临床试验终点，因为夜视受损是早期ARM的一个标志。一种新型暗适应计AdaptDx被用于评估ARM的检测。AdaptDx采用了一个为检测ARM而优化的20分钟方案。与正常成年人（N = 17）相比，ARM患者（N = 17）表现出明显的暗适应受损。诊断敏感性为88%，特异性为100%。AdaptDx的诊断测试特征与之前使用60至120分钟方案的研究相似。
