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侵袭性肺炎球菌病在脉络丛癌治疗后发生。

Invasive pneumococcal disease following treatment for choroid plexus carcinoma.

机构信息

Department of Haematology/Oncology, Great Ormond Street Hospital, London WC1N 3JH, UK.

出版信息

Support Care Cancer. 2010 May;18(5):647-50. doi: 10.1007/s00520-009-0804-2. Epub 2010 Jan 15.

DOI:10.1007/s00520-009-0804-2
PMID:20076974
Abstract

INTRODUCTION

A 13-month-old child was treated for choroid plexus carcinoma with partial embolisation, complete surgical excision and chemotherapy. The patient's course was complicated by the presence of chronic bilateral subdural collections.

CASE REPORT

Four months from completing treatment, the child presented with an empyema in the subdural space caused by Streptococcus pneumoniae subtype 6A.

DISCUSSION

The case highlights a number of questions about pneumococcal immunisation after standard chemotherapy. Evidence-based guidelines are required urgently to direct best practice.

摘要

引言

一名 13 个月大的儿童接受了脉络丛癌的部分栓塞、完全手术切除和化疗治疗。该患者的病程因存在慢性双侧硬脑膜下积液而变得复杂。

病例报告

在完成治疗后的 4 个月，患儿出现由 6A 型肺炎链球菌引起的硬脑膜下积脓。

讨论

该病例提出了一些关于标准化疗后肺炎球菌免疫接种的问题。迫切需要循证指南来指导最佳实践。

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Br J Haematol. 2009 Dec;147(5):700-5. doi: 10.1111/j.1365-2141.2009.07903.x. Epub 2009 Sep 18.
2
Randomized study of early versus late immunization with pneumococcal conjugate vaccine after allogeneic stem cell transplantation.异基因干细胞移植后早期与晚期接种肺炎球菌结合疫苗的随机研究。
Clin Infect Dis. 2009 May 15;48(10):1392-401. doi: 10.1086/598324.
3
Risks of invasive pneumococcal disease in children with underlying chronic diseases.
患有潜在慢性疾病儿童的侵袭性肺炎球菌疾病风险。
Pediatrics. 2008 Jul;122(1):e26-32. doi: 10.1542/peds.2007-1510.
4
Increased risk for invasive pneumococcal diseases in children with acute lymphoblastic leukaemia.
Br J Haematol. 2007 Jun;137(5):457-60. doi: 10.1111/j.1365-2141.2007.06601.x.
5
Revaccination of children after completion of standard chemotherapy for acute leukemia.急性白血病患儿完成标准化疗后的再次接种疫苗。
Clin Infect Dis. 2007 Mar 1;44(5):635-42. doi: 10.1086/511636. Epub 2007 Jan 24.
6
Pneumococcal conjugate vaccine provides early protective antibody responses in children after related and unrelated allogeneic hematopoietic stem cell transplantation.肺炎球菌结合疫苗在儿童进行相关和非相关异基因造血干细胞移植后可提供早期保护性抗体反应。
Blood. 2007 Mar 15;109(6):2322-6. doi: 10.1182/blood-2006-06-032284. Epub 2006 Nov 7.
7
Development and validation of a nonaplex assay for the simultaneous quantitation of antibodies to nine Streptococcus pneumoniae serotypes.一种用于同时定量检测针对九种肺炎链球菌血清型抗体的九联检测法的开发与验证。
J Immunol Methods. 2005 Jan;296(1-2):135-47. doi: 10.1016/j.jim.2004.11.006. Epub 2004 Dec 8.
8
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Arch Dis Child. 2003 Aug;88(8):712-4. doi: 10.1136/adc.88.8.712.
9
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Arch Dis Child. 2002 Jun;86(6):403-6. doi: 10.1136/adc.86.6.403.
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