Quantitation of fentanyl in blood and urine using gas chromatography-mass spectrometry (GC-MS).
作者信息
Goldberger Bruce A, Chronister Chris W, Merves Michele L
机构信息
Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, USA.
出版信息
Methods Mol Biol. 2010;603:245-52. doi: 10.1007/978-1-60761-459-3_22.
PMID:20077075
Abstract
Fentanyl is a potent, short-acting synthetic opioid analgesic. Fentanyl is measured in blood and urine following mixed-mode solid phase extraction. The specimens are fortified with deuterated internal standard and a five-point calibration curve is constructed. The final extracts are reconstituted in methanol and analyzed using selected ion monitoring gas chromatography-mass spectrometry.
摘要
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