McLean Hospital, Belmont, MA, United
Contemp Clin Trials. 2010 Mar;31(2):185-8. doi: 10.1016/j.cct.2010.01.002. Epub 2010 Jan 14.
Treatment research with opioid-dependent populations has not traditionally distinguished between those dependent on prescription opioids versus dependent upon heroin. Evidence suggests there is a substantial subpopulation of individuals with opioid dependence resulting largely or exclusively from prescription opioid use. Because this subpopulation may respond to treatment differently from heroin users, a method for discriminating DSM-IV opioid dependence due to prescription opioid use would provide more precision when examining this population. This paper describes an innovative method using a currently available diagnostic instrument, to diagnose DSM-IV opioid dependence and distinguish between dependence resulting from prescription opioids versus dependence upon heroin.
治疗研究表明，阿片类药物依赖人群中，依赖处方类阿片的人群和依赖海洛因的人群之间并无明显区别。有证据表明，有相当一部分阿片类药物依赖者主要或完全是由处方类阿片药物使用引起的。因为这个亚群对治疗的反应可能与海洛因使用者不同，所以在检查这一人群时，一种用于区分因处方类阿片药物使用导致的 DSM-IV 阿片类药物依赖的方法将提供更高的精确度。本文描述了一种使用现有诊断工具的创新方法，用于诊断 DSM-IV 阿片类药物依赖，并区分因处方类阿片药物使用导致的依赖和因海洛因使用导致的依赖。
