Schmidt S H, Hellström S
Department of Otorhinolaryngology, Head and Neck Surgery, University of Umeå, Sweden.
ORL J Otorhinolaryngol Relat Spec. 1991;53(1):32-6. doi: 10.1159/000276181.
In recent years, the rat has attracted increasing interest as an experimental animal in otological research. In the present study, the structure of the rat tympanic membrane (TM) is compared with that of a traditional experimental animal, the guinea pig, and with the human TM. The normal guinea pig TM consists mainly of a single layer of coarse fiber bundles, in contrast to the more solid layers of radial and circular fibers in man and rat. The investigation reveals similar architectural features in the rat and human TM, whereas the guinea pig TM differs structurally.
近年来，大鼠作为耳科学研究中的实验动物越来越受到关注。在本研究中，将大鼠鼓膜（TM）的结构与传统实验动物豚鼠以及人类的鼓膜结构进行了比较。正常豚鼠的鼓膜主要由单层粗纤维束组成，这与人类和大鼠中更坚实的放射状和环状纤维层不同。研究发现，大鼠和人类的鼓膜在结构特征上相似，而豚鼠的鼓膜在结构上则有所不同。
