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阻塞性睡眠呼吸暂停患者的头影测量钙化颈动脉粥样硬化斑块。

Cephalometric calcified carotid artery atheromas in patients with obstructive sleep apnea.

机构信息

Department of Oral Health Sciences, The University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, Canada.

出版信息

Sleep Breath. 2010 Dec;14(4):365-70. doi: 10.1007/s11325-009-0324-9. Epub 2010 Jan 19.

DOI:10.1007/s11325-009-0324-9
PMID:20084549
Abstract

BACKGROUND

In the progress of atherosclerosis, the carotid artery calcifies and sometimes appears as a calcified mass on a cephalometric radiograph.

PURPOSE

This study was designed to evaluate the prevalence of calcification in cephalometric radiographs of OSA patients and to identify the differences between subjects with and without carotid artery calcification.

METHODS

A total of 1,520 X-rays were evaluated. Data for group A, 508 traditional X-rays, were collected from the UBC Sleep Apnea Dental Clinic and data for group B, 1,012 digital X-rays, were obtained from the Tsuda Hospital in Japan. Subjects were divided into two groups according to whether or not calcification was present in the carotid artery area and the characteristic differences between these two groups were analyzed.

DISCUSSION

Group A had 34 (6.7%) subjects who exhibited calcification in the carotid arterial area, while group B had 96 (9.5%) subjects who revealed calcification. Group A calcification subjects had a significantly lower body mass index (BMI) than subjects who had no calcification (26.9 ± 3.2 vs. 29.7 ± 5.6, p<0.01). Group B calcification subjects were older than subjects who had no calcification (57.6 ± 12.6 vs. 49.8 ± 14.5, p<0.000). Previous reports have found the prevalence of calcification on X-rays of OSA patients to be higher than the prevalence of calcification found in the general population.

CONCLUSION

While the presence of a calcified mass on a cephalometric radiograph is not diagnostic of atherosclerosis, this information might help to aid in screening for the condition.

摘要

背景

在动脉粥样硬化的进展过程中,颈动脉会发生钙化,有时在头影测量 X 光片中会出现钙化肿块。

目的

本研究旨在评估 OSA 患者头影测量 X 光片中钙化的发生率,并确定有和无颈动脉钙化患者之间的差异。

方法

共评估了 1520 张 X 光片。组 A(508 张传统 X 光片)的数据来自不列颠哥伦比亚大学睡眠呼吸暂停牙科诊所,组 B(1012 张数字 X 光片)的数据来自日本筑波医院。根据颈动脉区域是否存在钙化将受试者分为两组,并分析两组之间的特征差异。

讨论

组 A 中有 34 名(6.7%)受试者的颈动脉区域出现钙化,而组 B 中有 96 名(9.5%)受试者出现钙化。组 A 钙化受试者的体重指数(BMI)明显低于无钙化受试者(26.9 ± 3.2 与 29.7 ± 5.6,p<0.01)。组 B 钙化受试者的年龄大于无钙化受试者(57.6 ± 12.6 与 49.8 ± 14.5,p<0.000)。以前的报告发现,OSA 患者 X 光片中钙化的发生率高于普通人群中钙化的发生率。

结论

虽然头影测量 X 光片中钙化肿块的存在不能诊断为动脉粥样硬化,但这些信息可能有助于筛查该疾病。

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