Faculty of Forensic Medicine, Zhongshan Medical School, Sun Yat-sen University, 74# Zhongshan Road II, Guangzhou, 510089, People's Republic of China.
Int J Legal Med. 2011 Jan;125(1):133-7. doi: 10.1007/s00414-009-0388-x. Epub 2010 Jan 20.
Nine non-combined DNA index system tetranucleotide short tandem repeat (STR) loci D2S1772, D6S1043, D7S3048, D8S1132, D11S2368, D12S391, D13S325, D18S1364, and GATA198B05 were amplified in a multiplex polymerase chain reaction system. The distribution of alleles of the nine STRs was reported from a Chinese Han population in Guangdong Province, Southern China. The combined power of exclusion in trios and duos for the nine loci was 0.999981 and 0.999025, respectively. Mutation rates range from 0 to 0.005618. Pairwise analysis of linkage disequilibrium, which included PowerPlex 16 System loci, did show statistically significant deviation from independence even though loci locate on the same chromosomes. The nine STRs are highly informative and suitable to extend the results obtained with other STRs commonly analyzed for difficult paternity and kinship analysis.
九个非组合 DNA 指数系统四核苷酸短串联重复(STR)基因座 D2S1772、D6S1043、D7S3048、D8S1132、D11S2368、D12S391、D13S325、D18S1364 和 GATA198B05 在多重聚合酶链反应系统中被扩增。这些 STR 的等位基因分布是从中国南方广东省的汉族人群中报告的。九个基因座的三人和二人联合排除概率分别为 0.999981 和 0.999025。突变率范围为 0 至 0.005618。尽管基因座位于同一染色体上,但连锁不平衡的成对分析确实显示出与独立性存在统计学上的显著偏差,包括 PowerPlex 16 系统基因座。这九个 STR 信息丰富,适合扩展其他常用于困难亲子关系和亲属关系分析的 STR 分析结果。