Unidad de Lípidos, Hospital Universitario Miguel Servet, Instituto Aragonés de Ciencias de la Salud (I+CS), Zaragoza, Spain.
Rev Esp Cardiol. 2010 Jan;63(1):97-102. doi: 10.1016/s1885-5857(10)70014-1.
Measurement of the carotid intima-media thickness enables arterial wall thickening to be quantified during preclinical disease stages. However, little is known about how the thickness varies in individuals with no cardiovascular risk factors. The objective of this study was to report on the range of carotid intima-media thicknesses observed in a population of healthy subjects with no cardiovascular risk factors and to identify parameters that influence it. The carotid intima-media thickness was assessed in 138 subjects (64 men and 74 women) aged 20-79 years whose age and sex were homogeneously distributed. The upper limit of normal for the mean carotid intima-media thickness ranged from 0.59-0.95 mm in men and from 0.52-0.93 mm in women. The upper limit for the maximum thickness varied from 0.81-1.11 mm in men and from 0.66-1.13 mm in women. The main parameters determining the intima-media thickness were age, male sex, systolic blood pressure and low-density lipoprotein cholesterol level.
颈动脉内膜中层厚度的测量可在临床前疾病阶段定量动脉壁增厚。然而，对于无心血管危险因素的个体，其厚度如何变化知之甚少。本研究的目的是报告无心血管危险因素的健康受试者的颈动脉内膜中层厚度范围，并确定影响其厚度的参数。在年龄和性别均匀分布的 138 名受试者（64 名男性和 74 名女性）中评估了颈动脉内膜中层厚度。男性颈动脉内膜中层厚度的平均值上限范围为 0.59-0.95 毫米，女性为 0.52-0.93 毫米。男性最大厚度上限范围为 0.81-1.11 毫米，女性为 0.66-1.13 毫米。决定内膜中层厚度的主要参数是年龄、男性性别、收缩压和低密度脂蛋白胆固醇水平。
