合成与抗原因子 4 对应的白色念珠菌细胞壁甘露聚糖的 3,6-支化寡甘露糖苷片段。
Synthesis of 3,6-branched oligomannoside fragments of the mannan from Candida albicans cell wall corresponding to the antigenic factor 4.
机构信息
Laboratory of Glycoconjugate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russia.
出版信息
Carbohydr Res. 2010 Jul 2;345(10):1283-90. doi: 10.1016/j.carres.2009.11.012. Epub 2009 Nov 12.
PMID:20096401
Abstract
3-Aminopropyl glycosides of 3,6-branched penta- and hexamannoside fragments of the cell wall mannan from Candida albicans, corresponding to the antigenic factor 4, have been synthesized. Subsequent coupling of both oligosaccharides with BSA using the squarate procedure provided corresponding neoglycoconjugates.
摘要
已合成了来自白色念珠菌细胞壁甘露聚糖的 3,6-支化五甘露糖和六甘露糖片段的 3-氨丙基糖苷，与抗原因子 4 相对应。随后使用 squarate 程序将这两种寡糖与 BSA 偶联，得到相应的糖结合物。
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