Maity Pallab, Hansda Dhananjay, Bandyopadhyay Uday, Mishra Dipak Kumar
Division of Drug Target Discovery and Development, Central Drug Research Institute, (CDRI), CSIR, Chatter Manzil Palace, Mahatma Gandhi Marg, Lucknow 226 001, India.
Indian J Exp Biol. 2009 Nov;47(11):849-61.
Bael (Aegle marmelos (L.) Corr.) is an important medicinal plant of India. Leaves, fruits, stem and roots of A. marmelos have been used in ethno medicine to exploit its' medicinal properties including astringent, antidiarrheal antidysenteric, demulcent, antipyretic and anti-inflammatory activities. Compounds purified from bael have been proven to be biologically active against several major diseases including cancer, diabetes and cardiovascular diseases. Preclinical studies indicate the therapeutic potential of crude extracts of A. marmelos in the treatment of many microbial diseases, diabetes and gastric ulcer. This review covers the biological activities of some isolated chemical constituents of A. marmelos and preclinical studies on some crude extracts and pure compounds to explore novel bioactive compounds for therapeutic application.
印度枳椇（Aegle marmelos (L.) Corr.）是印度一种重要的药用植物。印度枳椇的叶、果实、茎和根已被用于民族医学，以利用其药用特性，包括收敛、止泻、抗痢疾、缓和、解热和抗炎活性。从印度枳椇中纯化出的化合物已被证明对包括癌症、糖尿病和心血管疾病在内的几种主要疾病具有生物活性。临床前研究表明，印度枳椇粗提物在治疗多种微生物疾病、糖尿病和胃溃疡方面具有治疗潜力。本综述涵盖了印度枳椇一些分离化学成分的生物活性以及对一些粗提物和纯化合物的临床前研究，以探索用于治疗应用的新型生物活性化合物。
