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酸角(罗望子)及其植物化学物质在癌症的治疗和预防中的作用。

Aegle marmelos (L.) Correa (Bael) and its phytochemicals in the treatment and prevention of cancer.

机构信息

Father Muller Medical College, Mangalore, Karnataka, India.

出版信息

Integr Cancer Ther. 2013 May;12(3):187-96. doi: 10.1177/1534735412451320. Epub 2012 Oct 21.

DOI:10.1177/1534735412451320
PMID:23089553
Abstract

Aegle marmelos, commonly known as Bael and belonging to the family Rutaceae is an important medicinal plant in the traditional Indian system of medicine, the Ayurveda. The extract prepared by boiling the bark, leaves or roots in water is useful as laxative, febrifuge, and expectorant. The extract is also useful in ophthalmia, deafness, inflammations, catarrh, diabetes, and asthmatic complaints. The fruits are used in treating diarrhea, dysentery, stomach ache, and cardiac ailments. Scientific studies have validated many of Bael's ethnomedicinal properties and its potential antimicrobial effects, hypoglycemic, astringent, antidiarrheal, antidysenteric, demulcent, analgesic, anti-inflammatory, antipyretic, wound-healing, insecticidal, and gastroprotective properties. In addition, studies have also shown that Bael and some of the Bael phytochemicals possess antineoplastic, radioprotective, chemoprotective, and chemopreventive effects, properties efficacious in the treatment and prevention of cancer. For the first time, the current review summarizes the results related to these properties and emphasizes aspects that require further investigation for Bael's safe and effective use in the near future.

摘要

使君子,俗称“贝尔”,属于芸香科,是印度传统医学体系阿育吠陀中的一种重要药用植物。将树皮、叶子或根部煮沸制成的提取物可用作泻药、退烧药和解痰药。该提取物对眼炎、耳聋、炎症、卡他、糖尿病和哮喘也有疗效。果实用于治疗腹泻、痢疾、胃痛和心脏疾病。科学研究已经验证了使君子的许多民间医学特性及其潜在的抗菌作用、降血糖、收敛、抗腹泻、抗痢疾、缓和、镇痛、抗炎、退热、伤口愈合、杀虫和胃保护作用。此外,研究还表明,使君子和一些使君子植物化学物质具有抗肿瘤、辐射防护、化学保护和化学预防作用,这些作用对癌症的治疗和预防有效。本文首次总结了与这些特性相关的结果,并强调了需要进一步研究的方面,以便使君子在不久的将来能够安全有效地使用。

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