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浸润性导管乳腺癌的孤立性肾上腺转移:一种罕见的发现。

Solitary adrenal metastasis from invasive ductal breast cancer: an uncommon finding.

机构信息

Department of Breast Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou, Zhejiang, 310003, PR China.

出版信息

World J Surg Oncol. 2010 Jan 28;8:7. doi: 10.1186/1477-7819-8-7.

Abstract

BACKGROUND

Invasive ductal carcinoma (IDC) of the breast usually metastasizes to the lungs, liver, bones and brain. Solitary adrenal metastasis is extremely rare. Due to the rarity of this condition, the optimal treatment is unclear. We report the first case of IDC of the breast metastasizing solely to the adrenal gland after a modified radical mastectomy but having a long-term disease-free survival while treated merely by a left adrenalectomy.

CASE PRESENTATION

A 64-year-old woman was found a left adrenal mass on a follow-up visit two years after taking a right modified radical mastectomy for the breast cancer. She was subsequently given a left adrenalectomy. Postoperative histopathology findings were compatible with invasive ductal carcinoma (IDC) of the breast. Due to the patient's refusal, no further treatments were offered after the adrenalectomy. The patient now is still alive and has no sign of relapse. Survival time after taking the right modified radical mastectomy and the left adrenalectomy is more than five years and three years, respectively.

CONCLUSION

This is the first case of a patient with solitary, metachronous adrenal metastasis from IDC of the breast to be reported. For patients in this condition, complete removal of metastasized organ may translate into survival benefit.

摘要

背景

乳腺浸润性导管癌(IDC)通常转移到肺部、肝脏、骨骼和大脑。孤立性肾上腺转移极为罕见。由于这种情况很少见,因此最佳治疗方法尚不清楚。我们报告了首例乳腺 IDC 改良根治术后仅转移至肾上腺的病例,但仅通过左肾上腺切除术治疗后,患者长期无病生存。

病例介绍

一名 64 岁女性在接受右侧改良根治术治疗乳腺癌两年后随访时发现左侧肾上腺肿块。随后她接受了左肾上腺切除术。术后组织病理学检查结果符合乳腺浸润性导管癌(IDC)。由于患者拒绝,肾上腺切除术后未进行其他治疗。患者目前仍存活,无复发迹象。接受右侧改良根治术和左侧肾上腺切除术的生存时间分别超过五年和三年。

结论

这是首例报道的乳腺 IDC 孤立性、异时性肾上腺转移病例。对于这种情况的患者,转移器官的完全切除可能带来生存获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f674/2824745/d06b28e98a71/1477-7819-8-7-1.jpg

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