Puvvada Pragna, Nirhale Dakshayani S, Gaudani Romi H, Mane Praveen
General Surgery, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University) Pimpri, Pune, IND.
Cureus. 2024 Jul 29;16(7):e65635. doi: 10.7759/cureus.65635. eCollection 2024 Jul.
Adrenal gland metastasis is rare, often associated with invasive lobular carcinoma (ILC) rather than infiltrating ductal carcinoma (IDC). This report presents a case of a 43-year-old female with bilateral breast IDC and metastasis to the adrenal gland, with bilateral axillary and supraclavicular node involvement. Initial symptoms included a nipple discharge and a palpable lump. Diagnostic imaging and biopsy confirmed IDC, grade 2, with positive estrogen receptor (ER) and progesterone receptor (PR) status and negative human epidermal growth factor receptor 2 (HER2) status. The patient is undergoing chemotherapy and radiotherapy, with adrenalectomy planned post chemotherapy. The case underscores the need for early diagnosis and rapid treatment to improve outcomes, highlighting the paucity of data on managing solitary adrenal metastasis from IDC. Further research and clinical trials are essential to develop standardized treatment protocols.
肾上腺转移罕见,常与浸润性小叶癌(ILC)相关,而非浸润性导管癌(IDC)。本报告介绍了一例43岁女性,患有双侧乳腺IDC并伴有肾上腺转移,双侧腋窝及锁骨上淋巴结受累。初始症状包括乳头溢液和可触及肿块。诊断性影像学检查和活检确诊为2级IDC,雌激素受体(ER)和孕激素受体(PR)状态为阳性,人表皮生长因子受体2(HER2)状态为阴性。患者正在接受化疗和放疗,计划化疗后行肾上腺切除术。该病例强调了早期诊断和快速治疗以改善预后的必要性,突出了关于处理IDC孤立性肾上腺转移的数据匮乏。进一步的研究和临床试验对于制定标准化治疗方案至关重要。