Department of Family Medicine, University of Wisconsin-Madison, 1100 Delaplaine Court, Madison, Wisconsin 53715, USA.
J Stud Alcohol Drugs. 2010 Jan;71(1):23-31. doi: 10.15288/jsad.2010.71.23.
The aim of this study was to test the efficacy of brief physician advice in reducing alcohol use and related harm in college students.
The College Health Intervention Projects (CHIPs) is a randomized, controlled clinical trial with 12-month follow-up conducted in five college health clinics in Wisconsin; Washington state; and Vancouver, Canada. Of the 12,900 students screened for high-risk drinking, 484 men and 502 women met inclusion criteria and were randomized into a control (n = 493) or intervention (n = 493) group. Ninety-six percent of students participated in the follow-up procedures. The intervention consisted of two 15-minute counseling visits and two follow-up phone calls, and used motivational interviewing, contracting, diary cards, and take-home exercises.
No significant differences were found between groups at baseline on alcohol use, age, socioeconomic or smoking status, rates of depression, or measures of alcohol-related harm. At 12 months, the experimental subjects reduced their 28-day drinking totals by 27.2%, and the control group reduced their totals by 21%. A mixed effects repeated measures model found a statistical difference in favor of the brief-intervention group (beta = 4.7, SE = 2.0, p = .018) in 28-day drinking totals. The total Rutgers Alcohol Problem Index score was also significantly different during the 12-month follow-up period (beta = 0.8, SE = 0.4, p = .033). There was no difference on the other outcome measures of interest, such as frequency of excessive heavy drinking, health care utilization, injuries, drunk driving, depression, or tobacco use.
The study supports resource allocation and implementation of alcohol screening and brief physician advice in primary care-based college health clinics.
本研究旨在检验简短的医生建议在减少大学生饮酒和相关伤害方面的效果。
“大学生健康干预项目（CHIPs）”是一项在威斯康星州、华盛顿州和加拿大温哥华的五所大学健康诊所进行的随机、对照临床试验，为期 12 个月。在对 12900 名筛查出高危饮酒的学生进行评估后，484 名男性和 502 名女性符合纳入标准，并被随机分为对照组（n = 493）或干预组（n = 493）。96%的学生参与了随访程序。干预措施包括两次 15 分钟的咨询访问和两次随访电话，使用动机访谈、签约、日记卡和带回家的练习。
在基线时，两组间在饮酒量、年龄、社会经济地位或吸烟状况、抑郁发生率或酒精相关伤害衡量标准上无显著差异。在 12 个月时，实验组的 28 天饮酒总量减少了 27.2%，对照组减少了 21%。混合效应重复测量模型发现，简短干预组在 28 天饮酒总量方面具有统计学优势（β=4.7，SE=2.0，p=0.018）。在 12 个月的随访期间，Rutgers 酒精问题指数总分也存在显著差异（β=0.8，SE=0.4，p=0.033）。其他感兴趣的结果衡量标准，如过度大量饮酒的频率、医疗保健利用、伤害、酒后驾车、抑郁或吸烟，没有差异。
该研究支持在以初级保健为基础的大学健康诊所中分配资源并实施酒精筛查和医生简短建议。
