University of New South Wales, Sydney, New South Wales, Australia.
Emerg Infect Dis. 2010 Feb;16(2):297-300. doi: 10.3201/eid1602.081707.
Multilocus variable-number tandem-repeat analysis (MLVA) of 316 Bordetella pertussis isolates collected over 40 years from Australia and 3 other continents identified 66 MLVA types (MTs), including 6 predominant MTs. Typing of genes encoding acellular vaccine antigens showed changes that may be vaccine driven in 2 MTs prevalent in Australia.
对来自澳大利亚和其他三个大洲的 316 株百日咳博德特氏菌分离株进行多位点可变数目串联重复分析(MLVA),确定了 66 种 MLVA 型(MTs),包括 6 种主要 MTs。对编码无细胞疫苗抗原的基因进行分型显示,在澳大利亚流行的 2 种 MT 中,可能存在疫苗驱动的变化。