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表面活性剂对次氯酸钠溶液溶解猪牙髓组织的影响。

The effect of surfactant on the dissolution of porcine pulpal tissue by sodium hypochlorite solutions.

机构信息

School of Dentistry, University of Queensland, Brisbane, Queensland, Australia.

出版信息

J Endod. 2012 Sep;38(9):1257-60. doi: 10.1016/j.joen.2012.05.013. Epub 2012 Jun 20.

Abstract

INTRODUCTION

A previous study of the relative dental pulp-dissolving abilities of Milton brand of sodium hypochlorite (NaOCl) and other surfactant-containing NaOCl solutions produced specifically for endodontic treatment showed a markedly better performance of the surfactant-containing product that was not explained by differences in active chlorine content. This study investigated whether the presence of surfactant in the NaOCl solutions was responsible for the difference in dissolution times seen in the previous study.

METHODS

Circular samples 2.5 mm in diameter were punched out of the pulps of mandibular incisor teeth from young pigs. The 4 NaOCl solutions tested were Hypochlor 1% and Hypochlor 4% forte, which contained surfactant, and 2 identical solutions without surfactant. Twenty pulp specimens were immersed in 20 individual 25-mL aliquots of each of the 4 NaOCl solutions and observed while stirring until dissolution was complete. The time to dissolution of each sample was determined by stopwatch. Dissolution times for each solution were averaged and compared statistically in R (version 2.12.0) by using multiple regression with nominal active chlorine content as a covariate.

RESULTS

No statistical difference was detected between the dissolution times for either of the Hypochlor solutions with and without surfactant.

CONCLUSIONS

The addition of surfactant alone does not appear to improve the abilities of NaOCl to dissolve dental pulp tissue.

摘要

简介

先前对 Milton 牌次氯酸钠(NaOCl)和其他专为根管治疗配制的含表面活性剂 NaOCl 溶液的相对牙髓溶解能力的研究表明,含表面活性剂的产品性能明显更好,而这不能用有效氯含量的差异来解释。本研究旨在探讨 NaOCl 溶液中表面活性剂的存在是否是导致先前研究中溶解时间差异的原因。

方法

从小猪下颌切牙牙髓中冲出直径为 2.5 毫米的圆形样本。测试的 4 种 NaOCl 溶液为 Hypochlor 1%和 Hypochlor 4% forte,均含有表面活性剂,以及 2 种不含表面活性剂的相同溶液。将 20 个牙髓样本分别浸入 4 种 NaOCl 溶液的 20 个 25 毫升等分试样中,并在搅拌的同时进行观察,直至完全溶解。通过秒表确定每个样本的溶解时间。在 R(版本 2.12.0)中,使用包含名义有效氯含量作为协变量的多元回归,对每个溶液的溶解时间进行平均值和统计学比较。

结果

未发现有或没有表面活性剂的 Hypochlor 溶液的溶解时间有统计学差异。

结论

单独添加表面活性剂似乎不会提高 NaOCl 溶解牙髓组织的能力。

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