Institute of Medical Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, Wales, UK.
Fam Cancer. 2010 Sep;9(3):469-77. doi: 10.1007/s10689-010-9324-y.
It is well-recognised that receipt of cancer genetic risk information can evoke a mix of both positive and negative emotional responses. Objective risk itself is not necessarily predictive of emotional response to receipt of risk information and the Cue Adaptive Reasoning Account (CARA; Renner, 2004) suggests that that the degree to which level of risk is consistent with expectations may influence emotional responses. This paper reports a thematic analysis of the free-text data structured around responses to the three risk labels: average, moderate or high. Data is reported from both 123 women and 15 men, including those with a past or current cancer diagnosis. Reactions to risk information appear to be dependent upon participants' pre-conceived expectations about their level of cancer risk. Many average risk respondents questioned the accuracy of their result, whereas high risk information was often expected. Findings are discussed in relation to the CARA model and clinical implications.
人们普遍认识到,接收癌症遗传风险信息会引起积极和消极的情绪反应。客观风险本身并不一定能预测对风险信息的接收的情绪反应,而线索适应推理模型(CARA;Renner,2004)表明,风险水平与预期的一致性程度可能会影响情绪反应。本文报告了对围绕三个风险标签(平均、中度或高)的自由文本数据的主题分析。数据来自 123 名女性和 15 名男性,包括过去或现在有癌症诊断的人。对风险信息的反应似乎取决于参与者对自己癌症风险水平的先入为主的预期。许多处于平均风险的受访者对自己结果的准确性提出了质疑,而高风险信息则往往是预期的。研究结果将根据 CARA 模型和临床意义进行讨论。