Department of Physiology, University of Murcia, Spain.
J Physiol Biochem. 2009 Sep;65(3):315-28. doi: 10.1007/BF03180584.
Fructooligosaccharides (FOS) are oligosaccharides that occur naturally in plants such as onion, chicory, garlic, asparagus, banana, artichoke, among many others. They are composed of linear chains of fructose units, linked by beta (2-1) bonds. The number of fructose units ranges from 2 to 60 and often terminate in a glucose unit. Dietary FOS are not hydrolyzed by small intestinal glycosidases and reach the cecum structurally unchanged. There, they are metabolized by the intestinal microflora to form short-chain carboxylic acids, L -lactate, CO(2), hydrogen and other metabolites. FOS have a number of interesting properties, including a low sweetness intensity; they are also calorie free, non-cariogenic and are considered as soluble dietary fibre. Furthermore, FOS have important beneficial physiological effects such as low carcinogenicity, a prebiotic effect, improved mineral absorption and decreased levels of serum cholesterol, triacylglycerols and phospholipids. Currently FOS are increasingly included in food products and infant formulas due to their prebiotic effect stimulate the growth of nonpathogenic intestinal microflora. Their consumption increases fecal bolus and the frequency of depositions, while a dose of 4-15 g/day given to healthy subjects will reduce constipation, considered one of the growing problems of modern society, and newborns during the first months of life.
低聚果糖(FOS)是一种天然存在于洋葱、菊苣、大蒜、芦笋、香蕉、朝鲜蓟等植物中的低聚糖。它们由果糖单元的线性链组成,通过β(2-1)键连接。果糖单元的数量从 2 到 60 不等,通常以葡萄糖单元结尾。膳食 FOS 不会被小肠糖苷酶水解,而是结构完整地到达盲肠。在那里,它们被肠道微生物群代谢为短链羧酸、L-乳酸、CO2、氢气和其他代谢物。FOS 具有许多有趣的特性,包括低甜度;它们也是无热量、非致龋的,被认为是可溶性膳食纤维。此外,FOS 具有重要的有益生理作用,如低致癌性、益生元作用、改善矿物质吸收和降低血清胆固醇、三酰甘油和磷脂水平。目前,由于其益生元作用可刺激非致病性肠道微生物群的生长,FOS 越来越多地被添加到食品和婴儿配方中。它们的消费增加了粪便的体积和沉积频率,而健康受试者每天摄入 4-15 克可减少便秘,便秘被认为是现代社会日益严重的问题之一,新生儿在生命的头几个月也会出现便秘。