Biomedical Engineering and Biotechnology, University of Massachusetts at Lowell, 1 University Avenue, Lowell, MA 01854, USA.
Macromol Biosci. 2010 Mar 10;10(3):246-57. doi: 10.1002/mabi.200900274.
The functional properties of six distinct electrospun silk material groups were evaluated to assess conformational and biocompatible characteristics related to wound dressings. In a hydrated state, all six silk matrices exhibited absorption, water vapor transmission, oxygen permeation and enzymatic biodegradation suitable for full-thickness wound sites. Employing constrained drying techniques, silk concentration was a determinate factor influencing material structural properties related to the storage and distribution of such wound dressing systems. Subsequently, three electrospun silk models demonstrated ideal biomaterial properties with potential utility for wound dressings.
评估了六种不同的静电纺丝丝材料组的功能特性，以评估与伤口敷料相关的构象和生物相容性特征。在水合状态下，所有六种丝基质均表现出适合全层伤口部位的吸湿性、水蒸气透过性、氧气渗透性和酶生物降解性。采用约束干燥技术，丝浓度是影响与这些伤口敷料系统的储存和分配相关的材料结构特性的决定因素。随后，三种静电纺丝丝模型表现出理想的生物材料特性，具有用于伤口敷料的潜力。
