Department of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA.
Department of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, USA.
Int J Mol Sci. 2019 Dec 26;21(1):186. doi: 10.3390/ijms21010186.
The combination of protein and polysaccharides with magnetic materials has been implemented in biomedical applications for decades. Proteins such as silk, collagen, and elastin and polysaccharides such as chitosan, cellulose, and alginate have been heavily used in composite biomaterials. The wide diversity in the structure of the materials including their primary monomer/amino acid sequences allow for tunable properties. Various types of these composites are highly regarded due to their biocompatible, thermal, and mechanical properties while retaining their biological characteristics. This review provides information on protein and polysaccharide materials combined with magnetic elements in the biomedical space showcasing the materials used, fabrication methods, and their subsequent applications in biomedical research.
几十年来,蛋白质和多糖与磁性材料的结合已经在生物医学应用中得到了实现。在复合生物材料中,大量使用了蛋白质(如丝、胶原和弹性蛋白)和多糖(如壳聚糖、纤维素和藻酸盐)。这些材料的结构具有广泛的多样性,包括它们的主要单体/氨基酸序列,允许对其性能进行调节。由于这些复合材料具有生物相容性、热和机械性能,同时保留了它们的生物学特性,因此各种类型的复合材料都受到了高度重视。本文综述了生物医学领域中结合磁性元素的蛋白质和多糖材料,展示了所使用的材料、制备方法以及它们在生物医学研究中的后续应用。