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莱姆病表现为亚急性横贯性脊髓炎。

Lyme disease presenting as subacute transverse myelitis.

机构信息

Department of Neurology, Cukurova University School of Medicine, Adana, Turkey.

出版信息

Acta Neurol Belg. 2009 Dec;109(4):326-9.

Abstract

Lyme disease (borreliosis) is a systemic illness resulting from infection with the spirochete Borrelia burgdorferi. It is transmitted to humans by the bites of infected ticks belonging to several species of the genus Ixodes. After the bacteria enter the body via the dermis, most patients develop the early, localised form of Lyme disease, which is characterised by erythema migrans and influenza-like symptoms. This disease may also affect the heart, nervous system and joints. The neurological findings of this disease may include peripheral and central nervous system signs. A 21-year-old woman attended a family medicine outpatient clinic complaining of unexplained pain and muscle power loss in her lower extremities. The problem had started in her right leg 3 months earlier and worsened in the last week. She had a neurology consultation and was hospitalised. Her neurological examination revealed bilateral facial paralysis and sensory impairment. Immunoglobulin M antibody to B. burgdorferi was positive on Western blotting in both serum and cerebrospinal fluid. The patient was diagnosed with subacute neuroborreliosis and treated.

摘要

莱姆病(波状热)是一种全身性疾病,由感染伯氏疏螺旋体引起。它通过感染几种硬蜱属的蜱叮咬传播给人类。细菌通过真皮进入人体后,大多数患者会出现早期局部莱姆病,其特征是游走性红斑和流感样症状。这种疾病还可能影响心脏、神经系统和关节。这种疾病的神经系统表现可能包括周围和中枢神经系统体征。一名 21 岁的女性因下肢不明原因疼痛和肌肉无力到家庭医学门诊就诊。问题始于她的右腿,3 个月前开始,并在最后一周恶化。她进行了神经科会诊并住院。她的神经系统检查显示双侧面瘫和感觉障碍。血清和脑脊液的 Western blot 均显示免疫球蛋白 M 抗体对 B. burgdorferi 呈阳性。该患者被诊断为亚急性神经莱姆病并接受治疗。

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