Greater Green Triangle University Department of Rural Health, Flinders University and Deakin University, Warrnambool, VIC.
Med J Aust. 2010 Feb 1;192(3):127-32. doi: 10.5694/j.1326-5377.2010.tb03449.x.
To determine population lipid profiles, awareness of hyperlipidaemia and adherence to Australian lipid management guidelines.
Population survey in rural south-eastern Australia, 2004-2006.
Stratified random sample from the electoral roll. Data from 1274 participants (40%) aged 25-74 years were analysed.
Population mean total, low-density lipoprotein and high-density lipoprotein cholesterol (TC, LDL-C and HDL-C) and triglyceride (TG) concentrations, prevalence of dyslipidaemia, and treatment according to 2001 and 2005 Australian guideline target levels.
Population-adjusted mean TC, TG, LDL-C and HDL-C concentrations were 5.38 mmol/L (95% CI, 5.30-5.45), 1.50 mmol/L (95% CI, 1.43-1.56), 3.23 mmol/L (95% CI, 3.16-3.30) and 1.46 mmol/L (95% CI, 1.44-1.49), respectively. Prevalence of hypercholesterolaemia (TC > 5.5 mmol/L or on treatment) was 48%. Lipid-lowering medication use was reported by 12%. Seventy-seven of 183 participants with established cardiovascular disease (CVD) or diabetes were untreated, and of the 106 treated, 59% reached the target LDL-C. Of those without CVD or diabetes already treated, 38% reached target LDL-C, and 397 participants at high absolute risk did not receive primary prevention. Ninety-five per cent of treated individuals with CVD or diabetes and 86% of others treated had cholesterol measured in the previous year. Sixty-nine per cent of individuals at low risk aged over 45 years had their cholesterol measured within the previous 5 years.
A comprehensive national strategy for lowering mean population cholesterol is required, as is better implementation of absolute risk management guidelines - particularly in rural populations.
确定人群的血脂水平、对高脂血症的认知程度以及对澳大利亚血脂管理指南的遵循情况。
2004-2006 年在澳大利亚东南部农村进行的人群调查。
从选民名单中抽取分层随机样本。分析了 1274 名年龄在 25-74 岁的参与者(40%)的数据。
人群平均总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)及三酰甘油(TG)浓度、血脂异常的患病率以及根据 2001 年和 2005 年澳大利亚指南目标水平进行的治疗情况。
人群校正后的平均 TC、TG、LDL-C 和 HDL-C 浓度分别为 5.38mmol/L(95%可信区间,5.30-5.45)、1.50mmol/L(95%可信区间,1.43-1.56)、3.23mmol/L(95%可信区间,3.16-3.30)和 1.46mmol/L(95%可信区间,1.44-1.49)。高胆固醇血症(TC>5.5mmol/L 或正在治疗)的患病率为 48%。报告使用降脂药物的有 12%。183 例已有心血管疾病(CVD)或糖尿病的患者中,77 例未接受治疗,106 例接受治疗的患者中,59%达到 LDL-C 目标值。已经接受治疗的 CVD 或糖尿病患者中,38%达到 LDL-C 目标值,而 397 名高绝对风险的患者未接受一级预防。95%的 CVD 或糖尿病患者中接受治疗者和 86%的其他患者中接受治疗者,其胆固醇在过去一年中得到了检测。69%的低危年龄超过 45 岁者在过去 5 年内进行过胆固醇检测。
需要制定降低人群平均胆固醇水平的综合国家战略,还需要更好地执行绝对风险管理指南——特别是在农村地区。