J Am Geriatr Soc. 2009 Nov;57(11):2118-24. doi: 10.1111/j.1532-5415.2009.02523.x.
To compare subjective memory deficit (SMD) in older adults with and without dementia or depression across multiple centers in low- and middle-income countries (LAMICs).
Secondary analysis of data from 23 case control studies.
Twenty-three centers in India, Southeast Asia (including China), Latin America and the Caribbean, Nigeria, and Russia.
Two thousand six hundred ninety-two community-dwelling people aged 60 and older in one of three groups: people with dementia, people with depression, and controls free of dementia and depression.
SMD was derived from the Geriatric Mental State examination.
Median SMD frequency was lowest in participants without dementia (26.2%) and higher in those with depression (50.0%) and dementia (66.7%). Frequency of SMD varied between centers. Depression and dementia were consistently associated with SMD. Older age and hypochondriasis were associated with SMD only in subjects without dementia. In those with dementia, SMD was associated with better cognitive function, whereas the reverse was the case in controls.
Associations with SMD may differ between subjects with and without dementia living in LAMICs.
在中低收入国家（LMICs）的多个中心，比较痴呆或抑郁症患者与无痴呆或抑郁症的老年人之间的主观记忆缺陷（SMD）。
对来自 23 项病例对照研究的数据进行二次分析。
印度、东南亚（包括中国）、拉丁美洲和加勒比、尼日利亚和俄罗斯的 23 个中心。
60 岁及以上的 2692 名居住在社区的人群，分为三组：痴呆患者、抑郁患者和无痴呆和抑郁的对照组。
SMD 源自老年精神状态检查。
无痴呆者的 SMD 发生率中位数最低（26.2%），抑郁者（50.0%）和痴呆者（66.7%）较高。SMD 的频率在中心之间有所不同。抑郁和痴呆与 SMD 始终相关。在无痴呆者中，年龄较大和疑病症与 SMD 相关。在痴呆患者中，SMD 与更好的认知功能相关，而在对照组中则相反。
在 LMICs 中，患有和不患有痴呆的患者与 SMD 的关联可能不同。
