Department of Medical Oncology and Therapeutics Research, City of Hope, Duarte, CA 91010, USA.
J Am Geriatr Soc. 2009 Nov;57 Suppl 2(0 2):S246-9. doi: 10.1111/j.1532-5415.2009.02503.x.
There is no standard tool for assessing the "functional age" of an older adult with cancer, although it is widely recognized that chronological age does not capture the heterogeneous physiological and functional status of older adults. Integrating a "geriatric assessment" into oncology research and clinical practice would help fill this void. Geriatric assessment covers factors that predict morbidity and mortality in older adults, including functional status, comorbidity, cognition, psychological state, nutritional status, and social support. This assessment provides a broader overall understanding of individual characteristics that affect life expectancy. In addition, this assessment identifies areas of vulnerability in older adults for which further evaluation or intervention is indicated. This article will address the utility of a geriatric assessment in oncology practice, review data that attest to the benefits of the assessment, and issue a call for further research into how this assessment can be integrated into oncology care. Doing so will help develop targeted interventions and optimize cancer outcomes in this rapidly growing population.
目前尚无评估癌症老年患者“功能年龄”的标准工具,尽管人们普遍认为,年龄与老年人不同的生理和功能状态并不相符。将“老年评估”纳入肿瘤学研究和临床实践中,有助于填补这一空白。老年评估涵盖了预测老年人发病率和死亡率的因素,包括功能状态、合并症、认知、心理状态、营养状况和社会支持。这种评估提供了对影响预期寿命的个体特征的更全面的了解。此外,该评估还确定了老年人易受伤害的领域,需要进一步评估或干预。本文将讨论老年评估在肿瘤学实践中的应用,回顾证明该评估益处的数据,并呼吁进一步研究如何将该评估纳入肿瘤学治疗。这样做将有助于为这一快速增长的人群制定有针对性的干预措施并优化癌症治疗结果。