The School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Qual Life Res. 2010 Apr;19(3):435-43. doi: 10.1007/s11136-010-9597-5. Epub 2010 Feb 4.
This study compared the responsiveness and criterion-related validity of the Stroke Impact Scale (SIS) and Stroke-Specific Quality of Life Scale (SS-QOL) for patients after stroke rehabilitation.
The SIS and SS-QOL, along with five criterion measures-the Fugl-Meyer Assessment, the Motor Activity Log, the Functional Independence Measure, the Frenchay Activities Index, and the Nottingham Extended Activities of Daily Living Scale-were administered to 74 patients with stroke before and after a 3-week intervention. Responsiveness was examined using the Wilcoxon signed rank test and standardized response mean (SRM). Criterion-related validity was investigated using the Spearman correlation coefficient (rho).
Whereas the SS-QOL subscales were nonresponsive to changes, the SIS hand function showed medium responsiveness (SRM = .52, Wilcoxon Z = 4.24, P < .05). Responsiveness of the SIS total also was significantly larger than that of the SS-QOL total (SRM difference, .36; 95% confidence interval, .02-.71). Criterion validity of the SIS hand function was good (rho = .51-.68; P < .01), but that of the SS-QOL was only fair (rho = .25-.31; P < .05).
Because the SIS had better overall responsiveness and the SIS hand function showed medium responsiveness and good criterion validity, the SIS appears to be more suited for assessing changes after stroke rehabilitation.
本研究比较了脑卒中影响量表（SIS）和脑卒中特异性生活质量量表（SS-QOL）在脑卒中康复后的反应性和效标关联效度。
在 3 周干预前后，对 74 例脑卒中患者同时进行 SIS 和 SS-QOL 以及 5 项效标测量（Fugl-Meyer 评估、运动活动日志、功能独立性测量、Frenchay 活动指数和诺丁汉扩展日常生活活动量表）。采用 Wilcoxon 符号秩检验和标准化反应均值（SRM）来评估反应性。采用 Spearman 相关系数（rho）来研究效标关联效度。
虽然 SS-QOL 子量表对变化无反应，但 SIS 手功能显示出中度反应性（SRM=0.52，Wilcoxon Z=4.24，P<.05）。SIS 总分的反应性也明显大于 SS-QOL 总分（SRM 差值，0.36；95%置信区间，0.02-0.71）。SIS 手功能的效标效度良好（rho=0.51-0.68；P<.01），而 SS-QOL 的效标效度仅为中等（rho=0.25-0.31；P<.05）。
由于 SIS 具有更好的整体反应性，且 SIS 手功能具有中度反应性和良好的效标效度，因此 SIS 似乎更适合评估脑卒中康复后的变化。
