Aston University, School of Life and Health Sciences, Birmingham, UK.
J Refract Surg. 2010 Nov;26(11):858-62. doi: 10.3928/1081597X-20100114-04. Epub 2010 Jan 15.
To investigate the mechanism of action of the Tetraflex (Lenstec Kellen KH-3500) accommodative intraocular lens (IOL).
Thirteen eyes of eight patients implanted with the Tetraflex accommodating IOL for at least 2 years underwent assessment of their objective amplitude-of-accommodation by autorefraction, anterior chamber depth and pupil size with optical coherence tomography, and IOL flexure with aberrometry, each viewing a target at 0.0 to 4.00 diopters of accommodative demand.
Pupil size decreased by 0.62 ± 0.41 mm on increasing accommodative demand, but the Tetraflex IOL was relatively fixed in position within the eye. The ocular aberrations of the eye changed with increased accommodative demand, but not in a consistent manner among individuals. Those aberrations that appeared to be most affected were defocus, vertical primary and secondary astigmatism, vertical coma, horizontal and vertical primary and secondary trefoil, and spherical aberration.
Some of the reported near vision benefits of the Tetraflex accommodating IOL appear to be due to changes in the optical aberrations because of the flexure of the IOL on accommodative effort rather than forward movement within the capsular bag.
研究 Tetraflex（Lenstec Kellen KH-3500）调节型人工晶状体的作用机制。
对植入 Tetraflex 调节型人工晶状体至少 2 年的 8 例患者的 13 只眼进行客观调节幅度的评估，包括自动折射、前房深度和瞳孔大小的光学相干断层扫描，以及通过像差仪评估人工晶状体的弯曲度，每个目标的调节需求为 0.0 至 4.00 屈光度。
随着调节需求的增加，瞳孔大小平均减少 0.62 ± 0.41mm，但 Tetraflex 人工晶状体在眼内的位置相对固定。随着调节需求的增加，眼的像差发生变化，但个体之间的变化方式并不一致。似乎受影响最大的像差是离焦、垂直初级和次级散光、垂直彗差、水平和垂直初级和次级三叶草以及球差。
Tetraflex 调节型人工晶状体的一些报道的近视力获益可能是由于人工晶状体在调节努力时的弯曲引起的光学像差变化，而不是在囊袋内的向前运动。
