碳酸银促进的碳水化合物衍生物的简单、温和且区域选择性的苄基化方法。
A simple, mild, and regioselective method for the benzylation of carbohydrate derivatives promoted by silver carbonate.
机构信息
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Punjab, India.
出版信息
Carbohydr Res. 2010 Mar 30;345(5):559-64. doi: 10.1016/j.carres.2009.12.012. Epub 2010 Jan 14.
PMID:20129602
Abstract
A simple, mild, and regioselective method has been developed for the selective benzylation and p-methoxybenzylation of carbohydrate derivatives in high yields using Ag(2)CO(3) as the promoter. Benzylation of base-labile substrates, for which other reported methods are of little use, has been performed in high yields.
摘要
一种简单、温和且区域选择性的方法已经被开发出来，用于使用 Ag(2)CO(3)作为促进剂高效地对糖衍生物进行选择性苄基化和对甲氧基苄基化。对于那些其他报道的方法几乎没有用的碱性不稳定底物，也可以进行高效的苄基化。
Zotero 插件