Oryzomys couesi 与来自墨西哥的共生虫媒病毒的实验感染。
Experimental infections of Oryzomys couesi with sympatric arboviruses from Mexico.
机构信息
Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA.
出版信息
Am J Trop Med Hyg. 2010 Feb;82(2):350-3. doi: 10.4269/ajtmh.2010.09-0024.
Abstract
Coues rice rat (Oryzomys couesi), a species abundant throughout Central America, was evaluated experimentally for the ability to serve as an amplifying host for three arboviruses: Patois (Bunyaviridae, Orthobunyavirus), Nepuyo (Orthobunyavirus), and Venezuelan equine encephalitis virus subtype ID (Togaviridae, Alphavirus). These three viruses have similar ecologies and are known to co-circulate in nature. Animals from all three cohorts survived infection and developed viremia with no apparent signs of illness and long-lasting antibodies. Thus, O. couesi may play a role in the general maintenance of these viruses in nature.
摘要
库氏稻鼠（Oryzomys couesi）是中美洲广泛存在的物种，曾被评估是否有能力作为三种虫媒病毒（包括：Patois 病毒、Nepuyo 病毒和委内瑞拉马脑炎病毒亚型 ID）的扩增宿主。这三种病毒具有相似的生态，已知在自然界中共同循环。来自所有三个队列的动物都能存活下来并感染病毒，产生病毒血症，没有明显的疾病迹象和持久的抗体。因此，O. couesi 可能在这些病毒在自然界中的普遍存在中发挥作用。
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