卡塔卡马斯病毒，一种自然情况下与洪都拉斯的库氏稻鼠相关的汉坦病毒属病毒。
Catacamas virus, a hantaviral species naturally associated with Oryzomys couesi (Coues' oryzomys) in Honduras.
作者信息
Milazzo Mary L, Cajimat Maria N B, Hanson J Delton, Bradley Robert D, Quintana Miguel, Sherman Catalina, Velásquez Reina T, Fulhorst Charles F
机构信息
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0609, USA.
出版信息
Am J Trop Med Hyg. 2006 Nov;75(5):1003-10.
The primary objective of this study was to extend our knowledge of the geographical distribution, genetic diversity, and natural host associations of the hantaviruses indigenous to North America. Antibody to a hantavirus was found in 5 (20.8%) of 24 Coues' oryzomys (Oryzomys couesi) and none of 41 other rodents captured near the town of Catacamas in eastern Honduras, and a hantavirus was isolated from one of the antibody-positive Coues' oryzomys. Analyses of nucleotide and amino acid sequence data indicated that the viral isolate is a strain of a novel hantaviral species (proposed species name "Catacamas virus") that is phylogenetically most closely related to Bayou virus, a hantaviral species that is principally associated with Oryzomys palustris (marsh oryzomys) in the southeastern United States. Catacamas virus is the first evidence for the occurrence of a hantaviral species in Honduras and the first evidence that a hantaviral species is naturally associated with an Oryzomys species other than O. palustris.
本研究的主要目的是扩展我们对北美洲本土汉坦病毒的地理分布、遗传多样性以及自然宿主关联的认识。在洪都拉斯东部卡塔卡马斯镇附近捕获的24只科氏稻鼠（Oryzomys couesi）中，有5只（20.8%）检测出汉坦病毒抗体，而在其他41只啮齿动物中未检测到。从一只抗体呈阳性的科氏稻鼠中分离出了一种汉坦病毒。对核苷酸和氨基酸序列数据的分析表明，该病毒分离株是一种新型汉坦病毒物种（提议的物种名称为“卡塔卡马斯病毒”）的毒株，在系统发育上与河口病毒关系最为密切，河口病毒是一种主要与美国东南部的沼泽稻鼠（Oryzomys palustris）相关的汉坦病毒物种。卡塔卡马斯病毒是洪都拉斯存在汉坦病毒物种的首个证据，也是汉坦病毒物种与除沼泽稻鼠之外的稻鼠属物种自然关联的首个证据。
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