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Xenon consumption during general surgery: a retrospective observational study.普通外科手术中的氙气消耗：一项回顾性观察研究。
Med Gas Res. 2013 Jun 11;3(1):12. doi: 10.1186/2045-9912-3-12.
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A practical rule for optimal flows for xenon anaesthesia in a semi-closed anaesthesia circuit.半紧闭麻醉回路中氙气麻醉的最佳流量实用规则。
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Xenon-mediated neuroprotection in response to sustained, low-level excitotoxic stress.氙气介导的针对持续性低水平兴奋性毒性应激的神经保护作用。
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Nausea and Vomiting following Balanced Xenon Anesthesia Compared to Sevoflurane: A Post-Hoc Explorative Analysis of a Randomized Controlled Trial.与七氟醚相比，平衡氙气麻醉后恶心呕吐情况：一项随机对照试验的事后探索性分析
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本文引用的文献

1
Feasibility and safety of xenon compared with sevoflurane anaesthesia in coronary surgical patients: a randomized controlled pilot study.氙气与七氟醚麻醉用于冠状动脉手术患者的可行性和安全性：一项随机对照的初步研究。
Br J Anaesth. 2013 Sep;111(3):406-16. doi: 10.1093/bja/aet072. Epub 2013 Apr 11.
2
Early cognitive function, recovery and well-being after sevoflurane and xenon anaesthesia in the elderly: a double-blinded randomized controlled trial.老年人七氟烷和氙气麻醉后的早期认知功能、恢复情况及幸福感：一项双盲随机对照试验
Med Gas Res. 2011 May 18;1(1):9. doi: 10.1186/2045-9912-1-9.
3
aepEX monitor for the measurement of hypnotic depth in patients undergoing balanced xenon anaesthesia.aepEX 监测仪用于测量行平衡氙气麻醉患者的催眠深度。
Br J Anaesth. 2012 Jan;108(1):80-8. doi: 10.1093/bja/aer393. Epub 2011 Dec 2.
4
A practical rule for optimal flows for xenon anaesthesia in a semi-closed anaesthesia circuit.半紧闭麻醉回路中氙气麻醉的最佳流量实用规则。
Eur J Anaesthesiol. 2010 Jul;27(7):660-5. doi: 10.1097/EJA.0b013e328336ec3b.
5
Closed-circuit xenon delivery using a standard anesthesia workstation.使用标准麻醉工作站进行闭路氙气输送。
Anesth Analg. 2010 Jan 1;110(1):101-9. doi: 10.1213/ANE.0b013e3181be0e17. Epub 2009 Oct 27.
6
A closed-circuit neonatal xenon delivery system: a technical and practical neuroprotection feasibility study in newborn pigs.一种闭路式新生儿氙气输送系统：新生猪的技术与实用神经保护可行性研究
Anesth Analg. 2009 Aug;109(2):451-60. doi: 10.1213/ane.0b013e3181aa9550.
7
Xenon induces late cardiac preconditioning in vivo: a role for cyclooxygenase 2?氙气在体内诱导晚期心脏预处理：环氧化酶2的作用？
Anesth Analg. 2008 Dec;107(6):1807-13. doi: 10.1213/ane.Ob013e31818874bf.
8
Positron emission tomography study of regional cerebral blood flow and flow-metabolism coupling during general anaesthesia with xenon in humans.人体在氙气全身麻醉期间脑局部血流及血流-代谢耦合的正电子发射断层扫描研究
Br J Anaesth. 2008 May;100(5):667-75. doi: 10.1093/bja/aen036. Epub 2008 Mar 15.
9
Multicenter randomized comparison of xenon and isoflurane on left ventricular function in patients undergoing elective surgery.氙气与异氟烷对择期手术患者左心室功能影响的多中心随机对照研究
Anesthesiology. 2007 Mar;106(3):463-71. doi: 10.1097/00000542-200703000-00010.
10
Positron emission tomography study of regional cerebral metabolism during general anesthesia with xenon in humans.人类氙气全身麻醉期间脑局部代谢的正电子发射断层扫描研究
Anesthesiology. 2006 Nov;105(5):936-43. doi: 10.1097/00000542-200611000-00014.

普通外科手术中的氙气消耗：一项回顾性观察研究。

Xenon consumption during general surgery: a retrospective observational study.

作者信息

Stoppe Christian, Rimek Achim, Rossaint Rolf, Rex Steffen, Stevanovic Ana, Schälte Gereon, Fahlenkamp Astrid, Czaplik Michael, Bruells Christian S, Daviet Christian, Coburn Mark

机构信息

Department of Anaesthesiology, University Hospital, RWTH Aachen, Aachen, Germany.

Department of Intensive Care Medicine, University Hospital, RWTH Aachen, Aachen, Germany.

出版信息

Med Gas Res. 2013 Jun 11;3(1):12. doi: 10.1186/2045-9912-3-12.

DOI:10.1186/2045-9912-3-12
PMID:23758970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3733954/
Abstract

BACKGROUND

High costs still limits the widespread use of xenon in the clinical practice. Therefore, we evaluated xenon consumption of different delivery modes during general surgery.

METHODS

A total of 48 patients that underwent general surgery with balanced xenon anaesthesia were retrospectively analysed according to the mode of xenon delivery during maintenance phase (ECO mode, AUTO mode or MANUAL mode).

RESULTS

Xenon consumption was highest during the wash-in phase (9.4 ± 2.1l) and further decreased throughout maintenance of anaesthesia. Comparison of different xenon delivery modes revealed significant reduced xenon consumption during ECO mode (18.5 ± 3.7L (ECO) vs. 24.7 ± 11.5L (AUTO) vs. 29.6 ± 14.3L (MANUAL); p = 0.033). No differences could be detected with regard to anaesthetic depth, oxygenation or performance of anaesthesia.

CONCLUSION

The closed-circuit respirator Felix Dual offers effective reduction of xenon consumption during general surgery when ECO mode is used.

摘要

背景

高昂的成本仍然限制了氙气在临床实践中的广泛应用。因此，我们评估了普通外科手术中不同输送模式下的氙气消耗量。

方法

根据维持期氙气输送模式（ECO模式、AUTO模式或MANUAL模式），对48例行氙气平衡麻醉的普通外科手术患者进行回顾性分析。

结果

氙气消耗量在冲洗期最高（9.4±2.1升），并在麻醉维持过程中进一步下降。不同氙气输送模式的比较显示，ECO模式下氙气消耗量显著降低（ECO模式为18.5±3.7升，AUTO模式为24.7±11.5升，MANUAL模式为29.6±14.3升；p = 0.033）。在麻醉深度、氧合或麻醉效果方面未发现差异。

结论

当使用ECO模式时，闭路呼吸器Felix Dual可有效减少普通外科手术中的氙气消耗。