Eisenberg Michael L, Galusha Deron, Kennedy William A, Cullen Mark R
Department of Urology, Stanford University School of Medicine, Stanford, CA, USA.
Department of Obstetrics/Gynecology, Stanford University School of Medicine, Stanford, CA, USA.
World J Mens Health. 2018 Sep;36(3):176-182. doi: 10.5534/wjmh.180006. Epub 2018 Mar 22.
The risk-benefit profile of neonatal circumcision is not clear. Most studies have focused on urinary tract infections but other health sequelae have not been evaluated. While evidence supports benefits of circumcision, a lack of randomized trials has been cited as a weakness. National guidelines provide mixed recommendations regarding neonatal circumcision. We review the weight of evidence and utilize current statistical methodology on observational data to examine the risks and benefits of neonatal circumcision.
新生儿包皮环切术的风险效益情况尚不清楚。大多数研究集中在尿路感染方面,但其他健康后遗症尚未得到评估。虽然有证据支持包皮环切术的益处,但缺乏随机试验被认为是一个弱点。国家指南对新生儿包皮环切术给出了不一致的建议。我们回顾证据的权重,并利用当前针对观察性数据的统计方法来研究新生儿包皮环切术的风险和益处。