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腰椎减压手术及后路外侧融合内固定术后的预后预测因素。

Predictors of outcome after decompressive lumbar surgery and instrumented posterolateral fusion.

作者信息

Cobo Soriano Javier, Sendino Revuelta Marcos, Fabregate Fuente Martín, Cimarra Díaz Ignacio, Martínez Ureña Paloma, Deglané Meneses Roberto

机构信息

Servicio de Cirugía de la Columna Vertebral, Departamento de Cirugía Ortopédica y Traumatología, Hospital Ramón y Cajal, Ctra Colmenar Km 9.100, Madrid 28034, Spain.

出版信息

Eur Spine J. 2010 Nov;19(11):1841-8. doi: 10.1007/s00586-010-1284-2. Epub 2010 Feb 5.

Abstract

There has been no agreement among different authors on guidelines to specify the situations in which arthrodesis is justified in terms of results, risks and complications. The aim of this study was to identify preoperative predictors of outcome after decompressive lumbar surgery and instrumented posterolateral fusion. A prospective observational study design was performed on 203 consecutive patients. Potential preoperative predictors of outcome included sociodemographic factors as well as variables pertaining to the preoperative clinical situation, diagnosis, expectations and surgery. Separate multiple linear regression models were used to assess the association between selected predictors and outcome variables, defined as the improvement after 1 year on the visual analog scale (VAS) for back pain, VAS for leg pain, physical component scores (PCS) of SF-36 and Oswestry disability index (ODI). Follow-up was available for 184 patients (90.6%). Patients with higher educational level and optimistic preoperative expectations had a more favourable postoperative leg pain (VAS) and ODI. Smokers had less leg pain relief. Patients with better mental component score (emotional health) had greater ODI improvement. Less preoperative walking capacity predicted more leg pain relief. Patients with disc herniation had greater relief from back pain and more PCS and ODI improvement. More severe lumbar pain was predictive of less improvement on ODI and PCS. Age, sex, body mass index, analgesic use, surgeon, self-rated health, the number of decompressed levels and the length of fusion had no association with outcome. This study concludes that a higher educational level, optimistic expectations for improvement, the diagnosis of "disc herniation", less walking capacity and good emotional health may significantly improve clinical outcome. Smoking and more severe lumbar pain are predictors of worse results.

摘要

不同作者对于明确在结果、风险和并发症方面关节融合术合理适用情况的指导原则尚未达成一致。本研究的目的是确定减压性腰椎手术及器械辅助后外侧融合术后结果的术前预测因素。对203例连续患者进行了前瞻性观察研究设计。结果的潜在术前预测因素包括社会人口学因素以及与术前临床情况、诊断、期望和手术相关的变量。使用单独的多元线性回归模型来评估选定预测因素与结果变量之间的关联,结果变量定义为术后1年背痛视觉模拟量表(VAS)、腿痛VAS、SF-36身体成分评分(PCS)和Oswestry功能障碍指数(ODI)的改善情况。184例患者(90.6%)获得了随访。教育水平较高且术前期望乐观的患者术后腿痛(VAS)和ODI改善情况更佳。吸烟者腿痛缓解程度较低。心理成分评分(情绪健康)较好的患者ODI改善更大。术前步行能力较差预示着腿痛缓解更多。椎间盘突出症患者背痛缓解更明显,PCS和ODI改善更多。更严重的腰痛预示着ODI和PCS改善较少。年龄、性别、体重指数、镇痛药使用情况、外科医生、自评健康状况、减压节段数和融合长度与结果无关。本研究得出结论,较高的教育水平、对改善的乐观期望、“椎间盘突出症”的诊断、较差的步行能力和良好的情绪健康可能显著改善临床结果。吸烟和更严重的腰痛是结果较差的预测因素。

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