Batlles Garrido J, Torres-Borrego J, Bonillo Perales A, Rubí Ruiz T, González Jiménez Y, Momblán De Cabo J, Aguirre Rodríguez J, Jiménez Liria R, Losilla Maldonado A, Daza Torres M
Paediatric Pulmonology and Allergy Unit, Service of Paediatrics, Hospital Torrecárdenas, Almería, Spain.
Allergol Immunopathol (Madr). 2010 Jul-Aug;38(4):174-80. doi: 10.1016/j.aller.2009.10.008. Epub 2010 Feb 6.
Atopic eczema affects 5-10% of the Spanish paediatric population, and has increased in frequency over the last few decades, probably due to changes in the environment and lifestyle. Phase II of the ISAAC (International Study of Asthma and Allergies in Childhood) uses a standardised methodology to establish the prevalence of allergic disorders and factors linked to them in each centre.
To assess the prevalence and severity of atopic eczema, and to establish factors linked to atopic eczema in 10-11 year-old school children in the city of Almeria (South-East coast of Spain).
An ecological study was carried out as part of ISAAC II, using homologated questionnaires and allergic tests in 1143 schoolchildren. Statistic association was assessed by means of chi(2) test, and then logistic regression analysis was performed with the most significant variables from the univariant analysis.
The prevalence of atopic eczema was 11.4%. The risk factors found in the multiple logistic regression analysis were: personal antecedents of severe asthma (OR 19 CI 95% 1.35-266) and severe rhinitis (OR 7.7 CI 95% 1.79-33), fungi in bedroom during the first year of life (OR 4.2 CI 95% 1.17-15.1) and atopic eczema in one parent (OR 5.2 CI 95% 2.69-10.1).
The prevalence of atopic eczema is similar to that found in other studies within ISAAC Phase I. The most important risk factors for atopic eczema are family and personal history of other atopic diseases and the presence of fungi in the home.
特应性湿疹影响着5%至10%的西班牙儿童群体,且在过去几十年中发病率有所上升,这可能归因于环境和生活方式的变化。国际儿童哮喘和过敏研究(ISAAC)的第二阶段采用标准化方法来确定每个中心过敏性疾病的患病率及其相关因素。
评估西班牙东南部沿海城市阿尔梅里亚10至11岁学童中特应性湿疹的患病率和严重程度,并确定与特应性湿疹相关的因素。
作为ISAAC II的一部分,开展了一项生态学研究,对1143名学童使用了统一问卷和过敏测试。通过卡方检验评估统计关联性,然后对单变量分析中最显著的变量进行逻辑回归分析。
特应性湿疹的患病率为11.4%。多因素逻辑回归分析中发现的风险因素包括:重度哮喘个人史(比值比19,95%置信区间1.35 - 266)、重度鼻炎(比值比7.7,95%置信区间1.79 - 33)、一岁以内卧室中有真菌(比值比4.2,95%置信区间1.17 - 15.1)以及父母一方患有特应性湿疹(比值比5.2,95%置信区间2.69 - 10.1)。
特应性湿疹的患病率与ISAAC第一阶段其他研究中的结果相似。特应性湿疹最重要的风险因素是其他特应性疾病的家族史和个人史以及家中存在真菌。