Rabies Program, Poxvirus and Rabies Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333, USA.
Virus Res. 2010 May;149(2):197-210. doi: 10.1016/j.virusres.2010.01.018. Epub 2010 Feb 6.
During 2009, 616 bats representing at least 22 species were collected from 10 locations throughout Kenya. A new lyssavirus, named Shimoni bat virus (SHIBV), was isolated from the brain of a dead Commerson's leaf-nosed bat (Hipposideros commersoni), found in a cave in the coastal region of Kenya. Genetic distances and phylogenetic reconstructions, implemented for each gene and for the concatenated alignment of all five structural genes (N, P, M, G and L), demonstrated that SHIBV cannot be identified with any of the existing species, but rather should be considered an independent species within phylogroup II of the Lyssavirus genus, most similar to Lagos bat virus (LBV). Antigenic reaction patterns with anti-nucleocapsid monoclonal antibodies corroborated these distinctions. In addition, new data on the diversity of LBV suggests that this species may be subdivided quantitatively into three separate genotypes. However, the identity values alone are not considered sufficient criteria for demarcation of new species within LBV.
在 2009 年，从肯尼亚各地的 10 个地点共采集了 616 只蝙蝠，代表至少 22 个物种。从肯尼亚沿海地区一个洞穴中发现的一只死亡的 Commerson's 叶鼻蝠（Hipposideros commersoni）的脑组织中分离出了一种新的副粘病毒，命名为 Shimoni 蝙蝠病毒（SHIBV）。基于每个基因和五个结构基因（N、P、M、G 和 L）的串联排列的遗传距离和系统发育重建表明，SHIBV 不能与任何现有物种相识别，而应被视为副粘病毒属第二组的一个独立物种，与 Lagos 蝙蝠病毒（LBV）最为相似。与抗核衣壳单克隆抗体的抗原反应模式证实了这些区别。此外，关于 LBV 多样性的新数据表明，该物种可能在数量上分为三个不同的基因型。然而，仅身份值本身并不被认为是在 LBV 内划定新物种的充分标准。
