德国巴伐利亚州蝙蝠中博氏梭形螺旋体病毒的分子诊断检测
Molecular diagnostics for the detection of Bokeloh bat lyssavirus in a bat from Bavaria, Germany.
机构信息
Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute of Molecular Biology, WHO Collaborating Centre for Rabies Surveillance and Research, D-17493 Greifswald, Insel Riems, Germany.
出版信息
Virus Res. 2013 Nov 6;177(2):201-4. doi: 10.1016/j.virusres.2013.07.021. Epub 2013 Aug 7.
A brain sample of a Natterer's bat tested positive for rabies with classical virological techniques. Molecular techniques confirmed the presence of Bokeloh bat lyssavirus (BBLV) in Germany for the second time. Sequence analysis revealed a close genetic relationship to the initial German BBLV case. Using a TaqMan RT-PCR specific for BBLV viral RNA was detected in various other organs albeit with differences in the relative viral load.
经经典病毒学技术检测，一只囊喉墓蝠的脑组织样本呈狂犬病阳性。分子技术在德国第二次确认存在博氏 bat lyssavirus (BBLV)。序列分析显示，与首例德国 BBLV 病例存在密切的遗传关系。使用针对 BBLV 病毒 RNA 的 TaqMan RT-PCR 检测到，尽管相对病毒载量存在差异，但在其他各种器官中均检测到了 BBLV。
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