University of Alberta Microfungus Collection and Herbarium, Edmonton, Alberta, Canada.
Med Mycol. 2010 Mar;48(2):335-45. doi: 10.3109/13693780903225805.
Anamorphic members of the ascomycete family Trichocomaceae including Aspergillus, Penicillium, Paecilomyces, Geosmithia and Sagenomella have been reported from infections in canines. Six clinical isolates (five associated with infections in canines and one from a human source) demonstrated simple phialides producing conidia in long chains and were investigated for their potential relationship to Sagenomella chlamydospora, a known agent of canine disseminated mycosis. Phylogenetic analyses of internal transcribed spacer (ITS) and small subunit (SSU) region sequences revealed that all of the canine-associated isolates were distinct from Sagenomella species. The new anamorphic genus and species Phialosimplex caninus is described to accommodate the clinical isolates. Sagenomella chlamydospora and Sagenomella sclerotialis are transferred to the new genus as Phialosimplex chlamydosporus comb. nov. and Phialosimplex sclerotialis comb. nov.
从犬感染中分离出的曲霉科（Trichocomaceae）的有性型成员，包括曲霉属、青霉属、拟青霉属、地霉属和沙雷氏菌属，已被报道与犬感染有关。6 株临床分离株（5 株与犬感染有关，1 株来自人类）表现出简单的瓶梗，可产生长链分生孢子，并对其与沙雷氏菌属（Sagenomella）的关系进行了研究，沙雷氏菌属是一种已知的犬传播性真菌病的病原体。内部转录间隔区（ITS）和小亚基（SSU）区序列的系统发育分析表明，所有与犬相关的分离株均与沙雷氏菌属不同。新的无性型属和种拟青霉属（Phialosimplex）被描述为包含临床分离株。将沙雷氏菌属的沙雷氏菌（Sagenomella chlamydospora）和沙雷氏菌属的硬皮病菌（Sagenomella sclerotialis）转移到新属中，分别作为拟青霉属的沙雷氏菌（Phialosimplex chlamydosporus comb. nov.）和拟青霉属的硬皮病菌（Phialosimplex sclerotialis comb. nov.）。
