Marrero David G
Diabetes Translational Research Center, Indiana University School of Medicine, Demonstration and Education Division, Indianapolis, Indiana 46202, USA.
J Diabetes Sci Technol. 2009 Jul 1;3(4):756-60. doi: 10.1177/193229680900300423.
Type 2 diabetes mellitus is one of the major public health threats in the United States today, reaching epidemic rates. Epidemiological evidence suggests a strong link between obesity and the risk of developing diabetes. Increasing evidence demonstrates that lifestyle interventions can significantly delay or possibly prevent the onset of type 2 diabetes in persons with increased risk. Despite these findings, there remain important barriers to the translation of this research to the public health. These include identifying persons with an increased risk for developing the disease and the lack of easily accessible, cost-effective intervention programs. At least one study, however, has effectively implemented an evidenced-based intervention in community settings, suggesting that it may be possible to develop a model for the national scalability of primary prevention in the United States.
2型糖尿病是当今美国主要的公共卫生威胁之一，已达到流行程度。流行病学证据表明肥胖与患糖尿病风险之间存在紧密联系。越来越多的证据表明，生活方式干预可显著延缓或可能预防高危人群2型糖尿病的发病。尽管有这些发现，但将该研究成果转化为公共卫生措施仍存在重要障碍。这些障碍包括识别疾病高危人群以及缺乏易于获得且具成本效益的干预项目。然而，至少有一项研究已在社区环境中有效实施了循证干预，这表明有可能开发出一种在美国全国范围内可推广的一级预防模式。
