Hôpital de la Conception, Marseille, France.
Respiration. 2010;80(4):348-52. doi: 10.1159/000282493. Epub 2010 Feb 9.
Refractory hepatic hydrothorax poses a challenging therapeutic dilemma, as treatment options are limited. Herein, we describe the case of a 48-year-old lady with advanced cirrhosis and recurrent transudative pleural effusion despite a sodium-restricted diet, optimal diuretic therapy and transjugular intrahepatic portosystemic shunt. Given the patient's platelet and coagulation disorders, thoracoscopic pleurodesis was deemed unsafe. Instead, a tunneled pleural catheter (PleurX®) was inserted under local anesthesia. Pleural drainage was achieved at the time of catheter placement and subsequently according to the patient's symptoms. Symptomatic improvement and gradual decrease of drainage volumes were noted. Six months following placement of PleurX, methicillin-resistant Staphylococcus aureus cellulitis at the insertion site prompted catheter removal. No pleural effusion was seen on chest X-ray at that time. Subsequent follow-up revealed spontaneous pleurodesis, as no recurrence of pleural effusion was seen over a 6-month follow-up period. Very few data are available with regard to the use of indwelling pleural catheters for benign transudative pleural effusion, and more specifically hepatic hydrothorax. Herein, we present this novel potential indication of the indwelling pleural catheter and illustrate the successful clinical outcome.
难治性肝性胸水是一种具有挑战性的治疗难题,因为治疗选择有限。在此,我们描述了一例 48 岁女性的病例,她患有晚期肝硬化,尽管采用了低盐饮食、最佳利尿剂治疗和经颈静脉肝内门体分流术,但仍反复出现渗出性胸腔积液。鉴于患者的血小板和凝血功能障碍,胸腔镜胸膜固定术被认为是不安全的。因此,在局部麻醉下插入了经皮胸膜腔引流管(PleurX®)。在导管放置时和随后根据患者的症状进行了胸腔引流。观察到症状改善和引流体积逐渐减少。在放置 PleurX 后的 6 个月,由于插入部位耐甲氧西林金黄色葡萄球菌蜂窝织炎,促使导管取出。此时胸部 X 线片未见胸腔积液。随后的随访显示自发性胸膜固定,因为在 6 个月的随访期间没有发现胸腔积液复发。关于留置胸膜导管用于良性渗出性胸腔积液,特别是肝性胸水的应用,数据非常有限。在此,我们提出了留置胸膜导管的这一新的潜在适应证,并说明了成功的临床结果。