Kim Dae-Hyeong, Kim Yun-Soung, Amsden Jason, Panilaitis Bruce, Kaplan David L, Omenetto Fiorenzo G, Zakin Mitchell R, Rogers John A
Appl Phys Lett. 2009 Sep 28;95(13):133701. doi: 10.1063/1.3238552. Epub 2009 Sep 29.
Many existing and envisioned classes of implantable biomedical devices require high performance electronicssensors. An approach that avoids some of the longer term challenges in biocompatibility involves a construction in which some parts or all of the system resorbs in the body over time. This paper describes strategies for integrating single crystalline silicon electronics, where the silicon is in the form of nanomembranes, onto water soluble and biocompatible silk substrates. Electrical, bending, water dissolution, and animal toxicity studies suggest that this approach might provide many opportunities for future biomedical devices and clinical applications.
许多现有的和设想中的可植入生物医学设备都需要高性能的电子传感器。一种避免生物相容性方面一些长期挑战的方法是构建一种系统，其中部分或整个系统会随着时间在体内吸收。本文描述了将单晶硅电子器件（硅呈纳米膜形式）集成到水溶性和生物相容性丝绸基板上的策略。电学、弯曲、水溶和动物毒性研究表明，这种方法可能为未来的生物医学设备和临床应用提供许多机会。
