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二十五周年纪念文章:高性能生物降解半导体器件的材料。

25th anniversary article: materials for high-performance biodegradable semiconductor devices.

机构信息

Department of Materials Science and Engineering, Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.

出版信息

Adv Mater. 2014 Apr 2;26(13):1992-2000. doi: 10.1002/adma.201304821. Epub 2014 Feb 21.

DOI:10.1002/adma.201304821
PMID:24677058
Abstract

We review recent progress in a class of silicon-based electronics that is capable of complete, controlled dissolution when immersed in water or bio-fluids. This type of technology, referred to in a broader sense as transient electronics, has potential applications in resorbable biomedical devices, eco-friendly electronics, environmental sensors, secure hardware systems and others. New results reported here include studies of the kinetics of hydrolysis of nanomembranes of single crystalline silicon in bio-fluids and aqueous solutions at various pH levels and temperatures. Evaluations of toxicity using live animal models and test coupons of transient electronic materials provide some evidence of their biocompatibility, thereby suggesting potential for use in bioresorbable electronic implants.

摘要

我们回顾了一类在浸入水或生物流体时能够完全、受控溶解的硅基电子产品的最新进展。这种在更广泛意义上被称为瞬态电子学的技术,在可吸收生物医学设备、环保电子、环境传感器、安全硬件系统等方面具有潜在的应用。这里报告的新结果包括在不同 pH 值和温度的生物流体和水溶液中对单晶硅纳米膜水解动力学的研究。使用活体动物模型和瞬态电子材料的测试试件进行的毒性评估提供了一些它们生物相容性的证据,从而表明它们有可能用于可生物吸收的电子植入物。

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