Health Program, RAND Corporation, Santa Monica, CA 90407-2138, USA.
Psychol Med. 2010 Dec;40(12):2059-68. doi: 10.1017/S0033291710000176. Epub 2010 Feb 11.
Anxiety disorders are the most prevalent mental health disorders and are associated with substantial disability and reduced well-being. It is unknown whether the relative impact of different anxiety disorders is due to the anxiety disorder itself or to the co-occurrence with other anxiety disorders. This study compared the functional impact of combinations of anxiety disorders in primary care out-patients.
A total of 1004 patients with panic disorder (PD), generalized anxiety disorder (GAD), social anxiety disorder (SAD) or post-traumatic stress disorder (PTSD) provided data on their mental and physical functioning, and disability. Multivariate regressions compared functional levels for patients with different numbers and combinations of disorders.
Of the patients, 42% had one anxiety disorder only, 38% two, 16% three and 3% all four. There were few relative differences in functioning among patients with only one anxiety disorder, although those with SAD were most restricted in their work, social and home activities and those with GAD were the least impaired. Functioning levels tended to deteriorate as co-morbidity increased.
Of the four anxiety disorders examined, GAD appears to be the least disabling, although they all have more in common than in distinction when it comes to functional impairment. A focus on unique effects of specific anxiety disorders is inadequate, as it fails to address the more pervasive impairment associated with multiple anxiety disorders, which is the modal presentation in primary care.
焦虑障碍是最常见的精神健康障碍,与严重残疾和幸福感降低有关。目前尚不清楚不同焦虑障碍的相对影响是由于焦虑障碍本身还是与其他焦虑障碍同时发生所致。本研究比较了初级保健门诊中外来患者中不同焦虑障碍组合的功能影响。
共有 1004 名患有惊恐障碍(PD)、广泛性焦虑障碍(GAD)、社交焦虑障碍(SAD)或创伤后应激障碍(PTSD)的患者提供了他们的心理和身体功能以及残疾数据。多元回归比较了具有不同数量和组合障碍的患者的功能水平。
在患者中,42%只有一种焦虑障碍,38%有两种,16%有三种,3%有四种。只有一种焦虑障碍的患者在功能方面差异不大,尽管 SAD 患者在工作、社交和家庭活动方面受到的限制最大,而 GAD 患者受影响最小。随着共病的增加,功能水平趋于恶化。
在所检查的四种焦虑障碍中,GAD 似乎是最不致残的,尽管它们在功能障碍方面的共同点多于区别。关注特定焦虑障碍的独特影响是不够的,因为它无法解决与多种焦虑障碍相关的更普遍的损害,这是初级保健中更常见的表现。