Department of General Internal Medicine at University of Texas M D Anderson Cancer Center, Houston, USA.
Am J Public Health. 2010 Apr 1;100 Suppl 1(Suppl 1):S118-24. doi: 10.2105/AJPH.2009.162776. Epub 2010 Feb 10.
We sought to identify cross-sectional hepatitis B virus (HBV) and HCV prevalence among Asian Americans at a community health fair and to assess referral rates.
We determined HBV prevalence with hepatitis B surface antigen (HBsAg), antibodies to hepatitis B core antigen (anti-HBc), and antibodies to hepatitis B surface antigen (anti-HBs). We determined HCV prevalence with hepatitis C antibodies. Successful referral occurred when participants with HBV or HCV were contacted, medically evaluated, and given contact information of liver specialists for care.
Of 202 people screened, 118 were Asian Americans (65 Chinese and 39 Vietnamese). Twelve had chronic HBV with positive HBsAg. However, chronic HBV prevalence increased from 10.2% to 13.6% by concomitant HBsAg, anti-HBc, and anti-HBs testing. Prevalence of HCV was 6% overall but 15.4% among Vietnamese. Overall, 83% of patients with chronic HBV and 100% of patients with occult HBV or HCV were successfully referred.
Concomitant HBsAg, anti-HBc, and anti-HBs testing permits diagnosis of chronic, occult HBV infections missed by testing with HBsAg alone. Persons identified with HBV or HCV at community health fairs can be successfully referred.
我们旨在社区健康博览会上确定亚裔美国人的乙型肝炎病毒 (HBV) 和丙型肝炎病毒 (HCV) 横断面流行率，并评估转介率。
我们通过乙型肝炎表面抗原 (HBsAg)、乙型肝炎核心抗原抗体 (抗-HBc) 和乙型肝炎表面抗原抗体 (抗-HBs) 来确定 HBV 流行率。我们通过丙型肝炎抗体来确定 HCV 流行率。当有 HBV 或 HCV 的参与者被联系、进行医学评估并获得肝脏专家的联系方式以便进行治疗时，即成功转介。
在 202 名接受筛查的人中，有 118 名是亚裔美国人（65 名中国人和 39 名越南人）。有 12 人患有慢性 HBV，且 HBsAg 呈阳性。然而，通过同时进行 HBsAg、抗-HBc 和抗-HBs 检测，慢性 HBV 的流行率从 10.2%增加到 13.6%。总的 HCV 流行率为 6%，但越南人中有 15.4%。总体而言，83%的慢性 HBV 患者和 100%的隐匿性 HBV 或 HCV 患者都成功转介。
同时进行 HBsAg、抗-HBc 和抗-HBs 检测可诊断仅通过 HBsAg 检测遗漏的慢性隐匿性 HBV 感染。在社区健康博览会上发现的 HBV 或 HCV 患者可以成功转介。
